SCHEMBL1332136

SCHEMBL1332136

Cc1c(CC(=O)C(=O)O)[nH]c2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
MAPT P10636 4/20 0.50
KMT2A Q03164 3/20 0.50
KDM4E B2RXH2 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
MEN1 O00255 2/20 0.50
HPGD P15428 2/20 0.50
GAA P10253 1/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
HSD17B10 Q99714 2/20 0.47
DAO P14920 1/20 0.46
DDO Q99489 1/20 0.46
AHR P35869 1/20 0.46
SIRT1 Q96EB6 1/20 0.44
USP2 O75604 1/20 0.43
HTT P42858 1/20 0.43
RAB9A P51151 2/20 0.42
EGFR P00533 1/20 0.42
MITF O75030 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5499463 0.87 ALDH1A1 (0.61) ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2
SCHEMBL28819186 0.79 MAPT (0.46) ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2
SCHEMBL28819201 0.78 KDM4E (0.58) ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2
SCHEMBL28900980 0.77 KMT2A (0.61) ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2
SCHEMBL28819182 0.77 ALDH1A1 (0.54) ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2
SCHEMBL13301938 0.75 AHR (0.55) ALDH1A1MAPTKMT2AKDM4EHPGD
SCHEMBL28472093 0.75 OXER1 (0.61) ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2
SCHEMBL13485647 0.75 AHR (0.59) ALDH1A1MAPTKMT2AKDM4EMEN1
SCHEMBL28468727 0.74 OXER1 (0.63) ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2
SCHEMBL1917841 0.73 AHR (0.57) ALDH1A1MAPTHPGDGAAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109266662-B Gene cluster for biosynthesis of innovative mycin or ring-opening innovative mycin 中国医学科学院医药生物技术研究所 2020-07-24 CN claimed
CN-109266662-B Gene cluster for biosynthesis of innovative mycin or ring-opening innovative mycin 中国医学科学院医药生物技术研究所 2020-07-24 CN disclosed
US-9673030-B2 Computer readable storage mediums, methods and systems for normalizing chemical profiles in biological or medical samples detected by mass spectrometry EMORY UNIVERSITY (US) 2017-06-06 US disclosed
US-20110282587-A1 COMPUTER READABLE STORAGE MEDIUMS, METHODS AND SYSTEMS FOR NORMALIZING CHEMICAL PROFILES IN BIOLOGICAL OR MEDICAL SAMPLES DETECTED BY MASS SPECTROMETRY EMORY UNIVERSITY (US) 2011-11-17 US disclosed