Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819182 | 0.86 | ALDH1A1 (0.54) | KDM4ELMNAPKMHSD17B10MAPT | |
| SCHEMBL7836624 | 0.85 | MAPT (0.54) | KDM4ELMNAPKMHSD17B10MEN1 | |
| SCHEMBL16669624 | 0.84 | KDM4E (0.57) | KDM4ELMNAPKMHSD17B10MEN1 | |
| SCHEMBL29744098 | 0.83 | KDM4E (0.53) | KDM4ELMNAPKMHSD17B10MEN1 | |
| SCHEMBL28819186 | 0.82 | MAPT (0.46) | KDM4ELMNAHSD17B10MEN1MAPT | |
| SCHEMBL28819187 | 0.82 | KDM4E (0.52) | KDM4ELMNAHSD17B10MEN1MAPT | |
| SCHEMBL4534138 | 0.82 | KDM4E (0.55) | KDM4ELMNAPKMHSD17B10MEN1 | |
| SCHEMBL728638 | 0.82 | KDM4E (0.55) | KDM4ELMNAPKMHSD17B10MEN1 | |
| SCHEMBL735160 | 0.81 | KDM4E (0.54) | KDM4ELMNAPKMHSD17B10MEN1 | |
| SCHEMBL5499463 | 0.81 | ALDH1A1 (0.61) | KDM4ELMNAHSD17B10MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031541-B | Preparation method of 2-substituted 3-methylindole derivative | 太原理工大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-114031541-A | Preparation method of 2-substituted 3-methylindole derivative | 太原理工大学 | 2022-02-11 | — | — | CN | disclosed |