Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K3 | P46734 | 2/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.50 |
| ▸ | BTK | Q06187 | 1/20 | 0.50 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.50 |
| ▸ | NEK10 | Q6ZWH5 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29849579 | 0.85 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2MAPTDYRK1ADHODH | |
| SCHEMBL296952 | 0.85 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2MAPTDYRK1ADHODH | |
| SCHEMBL7673424 | 0.84 | LCK (0.46) | MAP2K3LCKMAP2K6BTKMAP3K19 | |
| SCHEMBL28279288 | 0.81 | MAP2K3 (0.53) | MAP2K3LCKMAP2K6BTKMAP3K19 | |
| SCHEMBL752001 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPTDHODHPDE10A | |
| SCHEMBL1332816 | 0.80 | POLB (0.50) | MAP2K3LCKMAP2K6BTKMAP3K19 | |
| SCHEMBL6079236 | 0.79 | HDAC8 (0.48) | ALDH1A1SMN1; SMN2MAPTDHODHPDE10A | |
| SCHEMBL6890781 | 0.78 | LCK (0.69) | MAP2K3LCKMAP2K6BTKMAP3K19 | |
| SCHEMBL30713425 | 0.76 | DHODH (0.46) | MAP2K3LCKMAP2K6BTKMAP3K19 | |
| SCHEMBL28149300 | 0.76 | ALDH1A1 (0.57) | MAP2K3LCKMAP2K6BTKMAP3K19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11712425-B2 | Immunoregulatory role of 3-OH-kynurenamine and uses thereof | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2023-08-01 | — | — | US | claimed |
| CN-114624343-B | Method for relatively quantifying 45 inflammations and immune metabolites in serum | 中国科学院大连化学物理研究所 | 2023-01-24 | — | — | CN | claimed |
| CN-114624343-A | Method for relative quantification of 45 inflammations and immune metabolites in serum | 中国科学院大连化学物理研究所 | 2022-06-14 | — | — | CN | claimed |
| US-20210008021-A1 | IMMUNOREGULATORY ROLE OF 3-OH-KYNURENAMINE AND USES THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2021-01-14 | — | — | US | claimed |
| WO-2019178013-A1 | IMMUNOREGULATORY ROLE OF 3-OH-KYNURENAMINE AND USES THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2019-09-19 | — | — | WO | claimed |
| US-11712425-B2 | Immunoregulatory role of 3-OH-kynurenamine and uses thereof | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2023-08-01 | — | — | US | disclosed |
| US-11712425-B2 | Immunoregulatory role of 3-OH-kynurenamine and uses thereof | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2023-08-01 | — | — | US | disclosed |
| US-11712425-B2 | Immunoregulatory role of 3-OH-kynurenamine and uses thereof | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2023-08-01 | — | — | US | disclosed |
| CN-114624343-B | Method for relatively quantifying 45 inflammations and immune metabolites in serum | 中国科学院大连化学物理研究所 | 2023-01-24 | — | — | CN | disclosed |
| CN-114624343-A | Method for relative quantification of 45 inflammations and immune metabolites in serum | 中国科学院大连化学物理研究所 | 2022-06-14 | — | — | CN | disclosed |
| US-20210008021-A1 | IMMUNOREGULATORY ROLE OF 3-OH-KYNURENAMINE AND USES THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2021-01-14 | — | — | US | disclosed |
| US-20210008021-A1 | IMMUNOREGULATORY ROLE OF 3-OH-KYNURENAMINE AND USES THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2021-01-14 | — | — | US | disclosed |
| US-6210970-B1 | Method of diagnosing or categorizing disorders from biochemical profiles | ESA, INC. | 2001-04-03 | — | — | US | disclosed |
| US-6194217-B1 | CREATING DATABASE OF ELECTRICAL SIGNAL PATTERNS REPRESENTATIVE OF FREQUENCY DISTRIBUTION OF ELECTRICALLY ACTIVE CONSTITUENTS OF BIOLOGICAL SAMPLES FROM DIAGNOSED AND HEALTHY INDIVIDUALS, THEN COMPARING TEST SAMPLES TO DATABASE | ESA, INC. | 2001-02-27 | — | — | US | disclosed |
| EP-0567564-B1 | Method for diagnosing disorders from biochemical profiles | ESA INC (US) | 1996-10-16 | — | — | EP | disclosed |
| EP-0567564-A1 | METHOD OF DIAGNOSING OR CATEGORIZING DISORDERS FROM BIOCHEMICAL PROFILES. | ESA INC (US) | 1993-11-03 | — | — | EP | disclosed |
| EP-0201591-B1 | METHOD FOR DEVELOPING PHARMACEUTICALS FOR TREATMENT OF DISORDERS | ESA, Inc. (US) | 1993-02-10 | — | — | EP | disclosed |
| WO-1992013273-A1 | METHOD OF DIAGNOSING OR CATEGORIZING DISORDERS FROM BIOCHEMICAL PROFILES | ESA, INC. (US) | 1992-08-06 | — | — | WO | disclosed |
| US-5104639-A | Analzing body fluid samples using electrochemical liquid chromatography, compraring measured concentration with other living organisms to identify differences in metabolic pathways and administering drugs to alter pathways | ESA, INC. (US) | 1992-04-14 | — | — | US | disclosed |
| US-4863873-A | Method for biological testing and/or developing pharmaceuticals for treatment of disorders | ESA, INC. (US) | 1989-09-05 | — | — | US | disclosed |