Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL752001 | 0.85 | ALDH1A1 (0.50) | MAPTSMN1; SMN2ALDH1A1BBOX1EGLN1 | |
| SCHEMBL296952 | 0.82 | ALDH1A1 (0.63) | MAPTSMN1; SMN2ALDH1A1MEN1LMNA | |
| SCHEMBL29849579 | 0.82 | ALDH1A1 (0.63) | MAPTSMN1; SMN2ALDH1A1MEN1LMNA | |
| SCHEMBL1332157 | 0.79 | MAP2K3 (0.50) | ACHEMAPTSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL29402079 | 0.71 | ALDH1A1 (0.59) | MAPTSMN1; SMN2ALDH1A1HSD17B10MEN1 | |
| SCHEMBL6783762 | 0.71 | ALDH1A1 (0.59) | MAPTSMN1; SMN2ALDH1A1HSD17B10MEN1 | |
| SCHEMBL6079707 | 0.71 | KDM4E (0.48) | MAPTSMN1; SMN2ALDH1A1MEN1POLB | |
| SCHEMBL2908831 | 0.70 | ALDH1A1 (0.62) | MAPTSMN1; SMN2ALDH1A1MAPK1KMT2A | |
| SCHEMBL5388884 | 0.70 | ALDH1A1 (0.57) | MAPTSMN1; SMN2ALDH1A1BBOX1EGLN1 | |
| SCHEMBL28149300 | 0.70 | ALDH1A1 (0.57) | ACHEMAPTSMN1; SMN2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | HDAC8 3239/4885HDAC6 752/4885HDAC7 754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.