Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 2/20 | 0.47 |
| ▸ | THRA | P10827 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | UNG | P13051 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | TACR2 | P21452 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SHBG | P04278 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2687626 | 0.91 | ESR1 (0.53) | THRATHRBUNGCYP3A4SPHK1 | |
| SCHEMBL13892858 | 0.91 | ESR1 (0.53) | THRATHRBUNGCYP3A4SPHK1 | |
| SCHEMBL2494330 | 0.88 | CYSLTR2 (0.49) | TRPM2THRATHRBUNGCYP3A4 | |
| SCHEMBL3372631 | 0.87 | HPGD (0.50) | CYP3A4CYP2D6CYP2C9SPHK1SPHK2 | |
| SCHEMBL3369663 | 0.87 | HPGD (0.50) | CYP3A4CYP2D6CYP2C9SPHK1SPHK2 | |
| SCHEMBL3427326 | 0.87 | HPGD (0.50) | CYP3A4CYP2D6CYP2C9SPHK1SPHK2 | |
| SCHEMBL13321988 | 0.87 | THRA (0.46) | THRATHRBUNGCYP3A4CYP2D6 | |
| SCHEMBL402791 | 0.84 | RARB (0.50) | THRATHRBUNGCYP3A4ESR1 | |
| SCHEMBL1033861 | 0.84 | HPGD (0.53) | ALDH1A1LMNATP53HSD17B10 | |
| SCHEMBL60134 | 0.83 | ESR1 (0.61) | THRATHRBUNGCYP3A4SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718760-B2 | π-Conjugated polymer and manufacturing method thereof | RICOH COMPANY, LTD. (JP) | 2010-05-18 | — | — | US | disclosed |