Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | UNG | P13051 | 3/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13892858 | 0.93 | ESR1 (0.53) | HSD17B10ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL2687626 | 0.93 | ESR1 (0.53) | HSD17B10ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL13769488 | 0.93 | RARB (0.56) | RARBHSD17B10TSHRALDH1A1MEN1 | |
| SCHEMBL11962222 | 0.91 | HSD17B10 (0.59) | RARBHSD17B10TSHRRAB9AALDH1A1 | |
| SCHEMBL15381069 | 0.91 | HSD17B10 (0.47) | RARBHSD17B10TSHRNPC1RAB9A | |
| SCHEMBL1033861 | 0.89 | HPGD (0.53) | HSD17B10NPC1RAB9AATMALDH1A1 | |
| SCHEMBL4820665 | 0.89 | RARB (0.59) | RARBHSD17B10TSHRNPC1RAB9A | |
| SCHEMBL19683443 | 0.87 | HPGD (0.47) | MEN1MAPTKMT2AGAAHPGD | |
| SCHEMBL5190113 | 0.87 | RARB (0.55) | RARBHSD17B10TSHRNPC1RAB9A | |
| SCHEMBL13133431 | 0.87 | RARB (0.55) | RARBHSD17B10TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9159927-B2 | Electroactive materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-10-13 | — | — | US | disclosed |
| US-8652655-B2 | Electroactive materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-18 | — | — | US | disclosed |
| US-20130193423-A1 | ELECTROACTIVE MATERIALS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-08-01 | — | — | US | disclosed |
| US-20120065432-A1 | ELECTROACTIVE MATERIALS | E.I DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-15 | — | — | US | disclosed |
| US-8063399-B2 | Electroactive materials | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-22 | — | — | US | disclosed |
| US-20110095269-A1 | ELECTROACTIVE MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065432-A1 | ELECTROACTIVE MATERIALS | NAT1, ADRA1D, ADRA1B | RARB 837/4885HSD17B10 835/4885TSHR 1671/4885 |
| US-20110095269-A1 | ELECTROACTIVE MATERIALS | NAT1, ADRA1D, ADRA1B | RARB 837/4885HSD17B10 835/4885TSHR 1671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.