Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | UNG | P13051 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | TACR2 | P21452 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18417183 | 0.94 | TRPV1 (0.47) | CYSLTR2CYSLTR1TRPA1TRPM2PLA2G1B | |
| SCHEMBL7537271 | 0.91 | HTR2A (0.54) | CYSLTR2CYSLTR1TRPA1TRPM2PLA2G1B | |
| SCHEMBL7537266 | 0.91 | HTR2A (0.54) | CYSLTR2CYSLTR1TRPA1TRPM2PLA2G1B | |
| SCHEMBL18675929 | 0.90 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1TRPA1TRPM2PLA2G1B | |
| SCHEMBL7539291 | 0.89 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1TRPA1TRPM2PLA2G1B | |
| SCHEMBL7539299 | 0.89 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1TRPA1TRPM2PLA2G1B | |
| SCHEMBL13322020 | 0.88 | TRPM2 (0.47) | TRPM2THRATHRBHTR2AUNG | |
| SCHEMBL3372631 | 0.87 | HPGD (0.50) | CYP3A4CYP2D6CYP2C9SPHK2SPHK1 | |
| SCHEMBL3427326 | 0.87 | HPGD (0.50) | CYP3A4CYP2D6CYP2C9SPHK2SPHK1 | |
| SCHEMBL3369663 | 0.87 | HPGD (0.50) | CYP3A4CYP2D6CYP2C9SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730101-B1 | ALKYLATED PANA AND DPA COMPOSITIONS | BASF SE (DE) | 2015-11-18 | — | — | EP | disclosed |
| US-8030259-B2 | Antioxidant; heat resistance; photostability mixture; stabilization of material | CIBA SPECIALITY CHEMICALS CORP. (US) | 2011-10-04 | — | — | US | disclosed |
| US-20080274925-A1 | Alkylated Pana and Dpa Compositions | CIBA SPECIALTY CHEMICALS CORP. | 2008-11-06 | — | — | US | disclosed |