Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 14/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | DPP3 | Q9NY33 | 2/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17754790 | 1.00 | CMA1 (0.48) | CMA1ITGB3ITGA2BMALT1DPP3 | |
| SCHEMBL13374058 | 0.95 | CMA1 (0.47) | CMA1ITGB3ITGA2BMALT1DPP3 | |
| SCHEMBL13863164 | 0.94 | CMA1 (0.47) | CMA1ITGB3ITGA2BMALT1REN | |
| SCHEMBL22127917 | 0.92 | CMA1 (0.48) | CMA1ITGB3ITGA2BMALT1REN | |
| SCHEMBL13323713 | 0.92 | CMA1 (0.48) | CMA1ITGB3ITGA2BMALT1REN | |
| SCHEMBL22127851 | 0.92 | CMA1 (0.48) | CMA1ITGB3ITGA2BMALT1REN | |
| SCHEMBL22127914 | 0.92 | CMA1 (0.48) | CMA1ITGB3ITGA2BMALT1REN | |
| SCHEMBL22127849 | 0.92 | CMA1 (0.48) | CMA1ITGB3ITGA2BMALT1REN | |
| SCHEMBL24372015 | 0.92 | CMA1 (0.51) | CMA1ITGB3ITGA2BREN | |
| SCHEMBL13323714 | 0.92 | CMA1 (0.51) | CMA1ITGB3ITGA2BREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9402839-B2 | Selective targeting agents for mitochondria | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2016-08-02 | — | — | US | disclosed |
| US-20150297578-A1 | Selective Targeting Agents for Mitochondria | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2015-10-22 | — | — | US | disclosed |
| US-9006186-B2 | Selective targeting agents for mitochondria | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2015-04-14 | — | — | US | disclosed |
| US-8748369-B2 | Use of targeted nitroxide agents in bone healing | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2014-06-10 | — | — | US | disclosed |
| US-20140107317-A1 | Selective Targeting Agents for Mitochondria | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2014-04-17 | — | — | US | disclosed |
| US-20130102626-A1 | TARGETED NITROXIDE AGENTS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2013-04-25 | — | — | US | disclosed |
| US-7718603-B1 | conjugate of active peptidyl fragment having a high affinity with mitochondria and a scavenger for reaction oxygen species, or an enzyme inhibitor of nitric oxide synthase; for drug delivering drugs, or biodrugs of various types; drug targets for treating hemorrhagic shock, cell death apoptosis | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2010-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107317-A1 | Selective Targeting Agents for Mitochondria | TRAP1, HSPE1, TFAM | CMA1 4633/4885ITGB3 3698/4885ITGA2B 3519/4885 |
| US-20150297578-A1 | Selective Targeting Agents for Mitochondria | TRAP1, HSPE1, TFAM | CMA1 4632/4885ITGB3 3683/4885ITGA2B 3508/4885 |
| US-20130102626-A1 | TARGETED NITROXIDE AGENTS | TXNRD2, TXN2, HSPE1 | CMA1 4885/4885ITGB3 4315/4885ITGA2B 3901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.