SCHEMBL1332462

SCHEMBL1332462

C=CC(=O)NCCCCCCCCCCCC(=O)O

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.63
ZDHHC2 Q9UIJ5 1/20 0.63
PRMT1 Q99873 1/20 0.61
ADRA1A P35348 1/20 0.57
MAPK1 P28482 2/20 0.50
ABCC4 O15439 1/20 0.50
MAPT P10636 1/20 0.50
TGM2 P21980 1/20 0.49
TSHR P16473 2/20 0.48
LMNA P02545 1/20 0.48
NFKB1 P19838 1/20 0.48
PMP22 Q01453 1/20 0.48
EPHX2 P34913 7/20 0.47
PLA2G2A P14555 1/20 0.47
POLB P06746 1/20 0.47
ALDH1A1 P00352 1/20 0.46
TDP1 Q9NUW8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1083120 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL1018405 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL16229524 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL1015381 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL1334526 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL15463341 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL1018444 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL1018094 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL707155 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL1017486 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8753686-B2 Surface-treating agents, surface-treated powders, and cosmetics comprising the same SHISEIDO CO., LTD. (JP) 2014-06-17 US disclosed
US-20110280946-A1 Surface-Treating Agents, Surface-Treated Powders, And Cosmetics Comprising The Same SHISEIDO CO., LTD. (JP) 2011-11-17 US disclosed
EP-2112179-B1 Surface-treated powders, and cosmetics comprising the same SHISEIDO CO LTD (JP) 2011-04-27 EP disclosed
CN-100584865-C Surface treatment agent, surface-treated powder, and cosmetic containing the surface-treated powder SHISEIDO CO LTD 2010-01-27 CN disclosed
EP-1803750-B1 USE OF A POLYMER FOR SURFACE-TREATING A POWDER SHISEIDO CO LTD (JP) 2009-12-09 EP disclosed
EP-2112179-A1 Surface-treated powders, and cosmetics comprising the same Shiseido Co., Ltd. (JP) 2009-10-28 EP disclosed
US-20080081029-A1 acrylic homopolymers or copolymers, that can provide excellent hydrophobicity to powders or cosmetics, and can improve its rinsability SHISEIDO CO., LTD. (JP) 2008-04-03 US disclosed
CN-101035819-A Surface treatment agent, surface-treated powder, and cosmetic containing the surface-treated powder SHISEIDO CO LTD (JP) 2007-09-12 CN disclosed
EP-1803750-A1 SURFACE-TREATING AGENT, SURFACE-TREATED POWDER, AND COSMETIC PREPARATION CONTAINING SAME Shiseido Company, Limited (JP) 2007-07-04 EP disclosed
EP-0213996-B1 RAMIFIED POLYMERS BASED ON LIPOPEPTIDES FORMING THERMOTROPIC AND LYOTROPIC LIQUID CRYSTALS, THEIR USE AND CORRESPONDING MONOMERS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1989-09-06 EP disclosed
US-4859753-A EMULSIFIERS, FOAMING AGENTS CENTRE NATIOONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1989-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080081029-A1 acrylic homopolymers or copolymers, that can provide excellent hydrophobicity to powders or cosmetics, and can improve its rinsability CHRM1, H1-0, H1-2 ZDHHC20 2867/4885ZDHHC2 3639/4885PRMT1 24/4885
US-20110280946-A1 Surface-Treating Agents, Surface-Treated Powders, And Cosmetics Comprising The Same CHRM1, H1-0, H1-2 ZDHHC20 2549/4885ZDHHC2 3408/4885PRMT1 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.