SCHEMBL1018444

SCHEMBL1018444

C=CC(=O)NCCCCCCC(=O)O

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.63
ZDHHC2 Q9UIJ5 1/20 0.63
PRMT1 Q99873 1/20 0.61
ADRA1A P35348 1/20 0.57
MAPK1 P28482 2/20 0.50
ABCC4 O15439 1/20 0.50
MAPT P10636 1/20 0.50
TGM2 P21980 1/20 0.49
TSHR P16473 2/20 0.48
LMNA P02545 1/20 0.48
NFKB1 P19838 1/20 0.48
PMP22 Q01453 1/20 0.48
EPHX2 P34913 7/20 0.47
PLA2G2A P14555 1/20 0.47
POLB P06746 1/20 0.47
ALDH1A1 P00352 1/20 0.46
TDP1 Q9NUW8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1083120 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL1018405 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL1332462 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL16229524 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL1015381 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL1334526 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL15463341 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL1018094 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL707155 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL1017486 1.00 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10119003-B2 Surfactant-based monolithic columns, methods for making the same, and methods for using the same GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2018-11-06 US claimed
US-20130240358-A1 Surfactant-Based Monolithic Columns, Methods for Making the Same, and Methods for Using the Same Gergia State University Research Foundation, Inc. (US) 2013-09-19 US claimed
US-20110086409-A1 Surfactant-Based Monolithic Columns, Methods for Making the Same, and Method for Using the Same NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2011-04-14 US claimed
EP-2271602-A2 SURFACTANT-BASED MONOLITHIC COLUMNS, METHODS FOR MAKING THE SAME, AND METHODS FOR USING THE SAME Georgia State University Research Foundation, Inc. (US) 2011-01-12 EP claimed
WO-2009151733-A2 SURFACTANT-BASED MONOLITHIC COLUMNS, METHODS FOR MAKING THE SAME, AND METHODS FOR USING THE SAME GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2009-12-17 WO claimed
WO-2009054609-A1 BONE REGENERATION MEMBRANE AND METHOD FOR MANUFACTURING BONE REGENERATION MEMBRANE MEGAGEN IMPLANT CO., LTD. (KR) 2009-04-30 WO claimed
WO-2007123495-A1 METHOD OF PATTERNING AND PRODUCT(S) OBTAINED THEREFROM NATIONAL UNIVERSITY OF SINGAPORE (SG) 2007-11-01 WO claimed
US-10919926-B2 Compound or salt thereof, natural killer T cell activator, and pharmaceutical composition KEIO UNIVERSITY (JP) 2021-02-16 US disclosed
US-10919926-B2 Compound or salt thereof, natural killer T cell activator, and pharmaceutical composition KEIO UNIVERSITY (JP) 2021-02-16 US disclosed
US-20200207798-A1 COMPOUND OR SALT THEREOF, NATURAL KILLER T CELL ACTIVATOR, AND PHARMACEUTICAL COMPOSITION KEIO UNIVERSITY (JP) 2020-07-02 US disclosed
US-20200207798-A1 COMPOUND OR SALT THEREOF, NATURAL KILLER T CELL ACTIVATOR, AND PHARMACEUTICAL COMPOSITION KEIO UNIVERSITY (JP) 2020-07-02 US disclosed
EP-3502755-A1 DISPLAY MEDIUM FOR ASSESSMENT AND METHOD FOR MANUFACTURING SAME Zeon Corporation (JP) 2019-06-26 EP disclosed
EP-3434684-A1 COMPOUND OR SALT THEREOF, NATURAL KILLER T CELL ACTIVATOR, AND PHARMACEUTICAL COMPOSITION Keio University (JP) 2019-01-30 EP disclosed
US-20090088343-A1 METHOD OF PATTERNING AND PRODUCT(S) OBTAINED THEREFROM NATIONAL UNIVERSITY OF SINGAPORE (SG) 2009-04-02 US disclosed
US-20080281014-A1 Nanosubstance-Containing Composition, Process for Producing the Same, and Composite Made With the Same MITSUBISHI RAYON CO., LTD. (JP) 2008-11-13 US disclosed
WO-2007123495-A1 METHOD OF PATTERNING AND PRODUCT(S) OBTAINED THEREFROM NATIONAL UNIVERSITY OF SINGAPORE (SG) 2007-11-01 WO disclosed
CN-101001912-A Nanosubstance-containing composition, method for producing same, and composite using same MITSUBISHI RAYON CO (JP) 2007-07-18 CN disclosed
EP-0181528-B1 ABRASION-RESISTANT ULTRAVIOLET-CURABLE COATINGS DeSOTO, INC. (US) 1988-04-20 EP disclosed
US-4600649-A Abrasion-resistant ultraviolet-curable coatings DESOTO, INC. (US) 1986-07-15 US disclosed
EP-0181528-A1 Abrasion-resistant ultraviolet-curable coatings DeSOTO, INC. (US) 1986-05-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110086409-A1 Surfactant-Based Monolithic Columns, Methods for Making the Same, and Method for Using the Same PORCN, STOM, SMURF1 ZDHHC20 759/4885ZDHHC2 271/4885PRMT1 2382/4885
US-20200207798-A1 COMPOUND OR SALT THEREOF, NATURAL KILLER T CELL ACTIVATOR, AND PHARMACEUTICAL COMPOSITION CD4, NFATC1, PBK ZDHHC20 567/4885ZDHHC2 1093/4885PRMT1 2389/4885
US-10919926-B2 Compound or salt thereof, natural killer T cell activator, and pharmaceutical composition CD4, NFATC1, PBK ZDHHC20 722/4885ZDHHC2 1333/4885PRMT1 2109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.