Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.63 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.63 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1083120 | 1.00 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1 | |
| SCHEMBL1018405 | 1.00 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1 | |
| SCHEMBL1332462 | 1.00 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1 | |
| SCHEMBL1015381 | 1.00 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1 | |
| SCHEMBL1334526 | 1.00 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1 | |
| SCHEMBL15463341 | 1.00 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1 | |
| SCHEMBL1018444 | 1.00 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1 | |
| SCHEMBL1018094 | 1.00 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1 | |
| SCHEMBL707155 | 1.00 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1 | |
| SCHEMBL1017486 | 1.00 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883877-B2 | Materials based on radically polymerizable N,O-functionalized acrylic acid hydroxamides | IVOCLAR VIVADENT AG (LI) | 2014-11-11 | — | — | US | disclosed |