SCHEMBL13325752

SCHEMBL13325752

Cc1ccn2cc(-c3ccc4ccccc4c3)nc2c1

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 7/20 0.70
TP53 P04637 3/20 0.70
NPC1 O15118 9/20 0.66
RAB9A P51151 9/20 0.66
KDM4E B2RXH2 7/20 0.66
PKM P14618 2/20 0.66
POLB P06746 2/20 0.64
GAA P10253 2/20 0.64
GFER P55789 1/20 0.64
KMT2A Q03164 1/20 0.64
ALDH1A1 P00352 6/20 0.57
MAPT P10636 3/20 0.57
HPGD P15428 2/20 0.56
LMNA P02545 1/20 0.56
MAPK1 P28482 1/20 0.54
NFKB1 P19838 1/20 0.53
NFKB2 Q00653 1/20 0.53
RELA Q04206 1/20 0.53
HRH3 Q9Y5N1 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL972459 0.88 SMN1; SMN2 (0.63) SMN1; SMN2TP53NPC1RAB9AKDM4E
SCHEMBL13325910 0.86 SMN1; SMN2 (0.93) SMN1; SMN2TP53NPC1RAB9AKDM4E
SCHEMBL13325899 0.85 SMN1; SMN2 (0.79) SMN1; SMN2TP53NPC1RAB9AKDM4E
SCHEMBL6393875 0.84 SMN1; SMN2 (0.79) SMN1; SMN2TP53NPC1RAB9AKDM4E
SCHEMBL1691995 0.83 SMN1; SMN2 (1.00) SMN1; SMN2TP53NPC1RAB9AKDM4E
SCHEMBL28615698 0.82 RAB9A (0.61) SMN1; SMN2TP53NPC1RAB9AKDM4E
SCHEMBL1691846 0.82 NPC1 (0.68) SMN1; SMN2TP53NPC1RAB9AKDM4E
SCHEMBL6389122 0.82 SMN1; SMN2 (0.74) SMN1; SMN2TP53NPC1RAB9AKDM4E
SCHEMBL13325743 0.81 RAB9A (0.68) SMN1; SMN2TP53NPC1RAB9AKDM4E
SCHEMBL29614084 0.81 RAB9A (0.68) SMN1; SMN2TP53NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184664-A Synthetic method of naphtho [1',2', 4,5] imidazo [1,2-a ] pyridine fluorescent compound 阜阳师范大学 2024-06-14 CN disclosed
US-7714319-B2 Organic thin film transistor IDEMITSU KOSAN CO., LTD. (JP) 2010-05-11 US disclosed
US-7714319-B2 Organic thin film transistor IDEMITSU KOSAN CO., LTD. (JP) 2010-05-11 US disclosed
US-20070120111-A1 Organic thin film transistor IDEMITSU KOSAN CO., LTD. (JP) 2007-05-31 US disclosed
US-20070120111-A1 Organic thin film transistor IDEMITSU KOSAN CO., LTD. (JP) 2007-05-31 US disclosed