SCHEMBL972459

SCHEMBL972459

Cc1ccn2cc(-c3ccc(-c4c5ccccc5c(-c5ccc6ccccc6c5)c5ccccc45)cc3)nc2c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.63
TP53 P04637 1/20 0.63
NPC1 O15118 10/20 0.60
RAB9A P51151 9/20 0.60
KDM4E B2RXH2 6/20 0.60
PKM P14618 2/20 0.60
GAA P10253 2/20 0.52
POLB P06746 2/20 0.52
GFER P55789 1/20 0.52
KMT2A Q03164 1/20 0.52
HPGD P15428 3/20 0.52
LMNA P02545 1/20 0.52
HRH3 Q9Y5N1 4/20 0.48
MAPT P10636 3/20 0.47
ALDH1A1 P00352 6/20 0.47
NFKB1 P19838 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
MAPK1 P28482 2/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13325752 0.88 SMN1; SMN2 (0.70) SMN1; SMN2TP53NPC1RAB9AKDM4E
SCHEMBL13454279 0.85 SCD (0.50) SMN1; SMN2TP53NPC1RAB9AKDM4E
SCHEMBL973498 0.85 NPC1 (0.60) SMN1; SMN2TP53NPC1RAB9AKDM4E
SCHEMBL973176 0.85 RAB9A (0.57) SMN1; SMN2TP53NPC1RAB9AKDM4E
SCHEMBL13454313 0.84 SCD (0.49) SMN1; SMN2TP53NPC1RAB9AKDM4E
SCHEMBL18288733 0.84 SCD (0.51) SMN1; SMN2TP53NPC1RAB9AKDM4E
SCHEMBL971054 0.84 RAB9A (0.56) SMN1; SMN2TP53NPC1RAB9AKDM4E
SCHEMBL13454306 0.84 RAB9A (0.56) SMN1; SMN2TP53NPC1RAB9AKDM4E
SCHEMBL785387 0.82 ALDH1A3 (0.57) SMN1; SMN2TP53NPC1RAB9AKDM4E
SCHEMBL13325910 0.81 SMN1; SMN2 (0.93) SMN1; SMN2TP53NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10297760-B2 Organic electroluminescent element, compound and material for organic electroluminescent element, used in the same, and light emitting device, display device and illumination device, using the element UDC IRELAND LIMITED (IE) 2019-05-21 US disclosed
US-20180102483-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, USED IN THE SAME, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE AND ILLUMINATION DEVICE, USING THE ELEMENT UDC IRELAND LTD (IE) 2018-04-12 US disclosed
US-20180102483-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, USED IN THE SAME, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE AND ILLUMINATION DEVICE, USING THE ELEMENT UDC IRELAND LTD (IE) 2018-04-12 US disclosed
US-9812650-B2 Organic electroluminescent element, compound and material for organic electroluminescent element, used in the same, and light emitting device, display device and illumination device, using the element UDC IRELAND LIMITED (IE) 2017-11-07 US disclosed
US-9812650-B2 Organic electroluminescent element, compound and material for organic electroluminescent element, used in the same, and light emitting device, display device and illumination device, using the element UDC IRELAND LIMITED (IE) 2017-11-07 US disclosed
US-9728726-B2 Organic electroluminescent element, material for organic electroluminescent element and light emitting device, display device, and illumination device, each employing organic electroluminescent element UDC IRELAND LIMITED (IE) 2017-08-08 US disclosed
US-9728726-B2 Organic electroluminescent element, material for organic electroluminescent element and light emitting device, display device, and illumination device, each employing organic electroluminescent element UDC IRELAND LIMITED (IE) 2017-08-08 US disclosed
US-9608207-B2 Organic electroluminescence element UDC IRELAND LIMITED (IE) 2017-03-28 US disclosed
US-20150076462-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, USED IN THE SAME, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE AND ILLUMINATION DEVICE, USING THE ELEMENT UDC IRELAND LIMITED (IE) 2015-03-19 US disclosed
US-20150076462-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, USED IN THE SAME, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE AND ILLUMINATION DEVICE, USING THE ELEMENT UDC IRELAND LIMITED (IE) 2015-03-19 US disclosed
US-20140299851-A1 Organic Electroluminescence Element UDC IRELAND LIMITED (IE) 2014-10-09 US disclosed
US-20140291660-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element and Light Emitting Device, Display Device, and Illumination Device, Each Employing Organic Electroluminescent Element UDC IRELAND LIMITED (IE) 2014-10-02 US disclosed
US-20140291660-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element and Light Emitting Device, Display Device, and Illumination Device, Each Employing Organic Electroluminescent Element UDC IRELAND LIMITED (IE) 2014-10-02 US disclosed
US-7867629-B2 Nitrogenous heterocyclic derivative and organic electroluminescent element employing the same IDEMITSU KOSAN CO., LTD. (JP) 2011-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10297760-B2 Organic electroluminescent element, compound and material for organic electroluminescent element, used in the same, and light emitting device, display device and illumination device, using the element RPS10, RPS20, RPS19 SMN1; SMN2 903/4885TP53 3906/4885NPC1 4256/4885
US-20180102483-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, USED IN THE SAME, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE AND ILLUMINATION DEVICE, USING THE ELEMENT RPS10, RPS20, RPS19 SMN1; SMN2 903/4885TP53 3906/4885NPC1 4256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.