SCHEMBL13325865

SCHEMBL13325865

COc1ccc(-c2ncc3ccccn23)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 1.00
ALDH1A1 P00352 10/20 1.00
RAB9A P51151 8/20 1.00
HPGD P15428 5/20 1.00
MEN1 O00255 5/20 1.00
KMT2A Q03164 5/20 1.00
SMN1; SMN2 Q16637 3/20 1.00
HSD17B10 Q99714 2/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
MAPT P10636 6/20 0.68
CHEK1 O14757 1/20 0.68
LIMK1 P53667 1/20 0.68
MAPK14 Q16539 1/20 0.68
TDP1 Q9NUW8 1/20 0.68
NPC1 O15118 5/20 0.65
MAPK1 P28482 2/20 0.65
POLB P06746 1/20 0.48
USP7 Q93009 1/20 0.47
TUBB4A P04350 1/20 0.43
TUBB P07437 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13325866 0.83 ALDH1A1 (0.77) KDM4EALDH1A1RAB9AHPGDMEN1
SCHEMBL11534549 0.81 KDM4E (1.00) KDM4EALDH1A1RAB9AHPGDMEN1
SCHEMBL13325867 0.79 MEN1 (1.00) KDM4EALDH1A1RAB9AHPGDMEN1
SCHEMBL948580 0.77 KDM4E (0.77) KDM4EALDH1A1RAB9AHPGDMEN1
SCHEMBL22718492 0.76 KDM4E (0.61) KDM4EALDH1A1RAB9AHPGDMEN1
SCHEMBL13325870 0.76 KDM4E (0.65) KDM4EALDH1A1RAB9AHPGDMEN1
SCHEMBL31215225 0.75 MEN1 (0.69) KDM4EALDH1A1RAB9AHPGDMEN1
SCHEMBL26459346 0.73 RAB9A (0.57) KDM4EALDH1A1RAB9AHPGDMEN1
SCHEMBL8339561 0.73 KDM4E (0.61) KDM4EALDH1A1RAB9AHPGDMEN1
SCHEMBL17478115 0.72 HRH3 (0.57) KDM4EALDH1A1RAB9AHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7714319-B2 Organic thin film transistor IDEMITSU KOSAN CO., LTD. (JP) 2010-05-11 US disclosed
US-7714319-B2 Organic thin film transistor IDEMITSU KOSAN CO., LTD. (JP) 2010-05-11 US disclosed
US-20070120111-A1 Organic thin film transistor IDEMITSU KOSAN CO., LTD. (JP) 2007-05-31 US disclosed
US-20070120111-A1 Organic thin film transistor IDEMITSU KOSAN CO., LTD. (JP) 2007-05-31 US disclosed