SCHEMBL13325871

SCHEMBL13325871

c1ccc(-c2ncc3ccccn23)nc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 13/20 0.61
ALDH1A1 P00352 10/20 0.61
MAPT P10636 6/20 0.61
TDP1 Q9NUW8 3/20 0.61
CHEK1 O14757 1/20 0.61
LIMK1 P53667 1/20 0.61
MAPK14 Q16539 1/20 0.61
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
RAB9A P51151 5/20 0.54
MAPK1 P28482 3/20 0.54
NPC1 O15118 3/20 0.54
HSD17B10 Q99714 3/20 0.53
POLB P06746 2/20 0.53
HPGD P15428 6/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
TP53 P04637 2/20 0.46
TSHR P16473 1/20 0.46
LMNA P02545 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16796325 0.81 KDM4E (0.65) KDM4EALDH1A1MAPTTDP1CHEK1
SCHEMBL20610586 0.76 ALDH1A1 (0.55) KDM4EALDH1A1MAPTTDP1CHEK1
SCHEMBL11534549 0.76 KDM4E (1.00) KDM4EALDH1A1MAPTTDP1CHEK1
SCHEMBL948580 0.75 KDM4E (0.77) KDM4EALDH1A1MAPTTDP1CHEK1
SCHEMBL28467198 0.73 ALDH1A1 (0.54) KDM4EALDH1A1MAPTTDP1CHEK1
SCHEMBL11013773 0.71 SMN1; SMN2 (0.55) KDM4EALDH1A1MAPTTDP1KMT2A
SCHEMBL30498963 0.71 SMN1; SMN2 (0.55) KDM4EALDH1A1MAPTTDP1KMT2A
SCHEMBL13325866 0.71 ALDH1A1 (0.77) KDM4EALDH1A1MAPTTDP1CHEK1
SCHEMBL21239873 0.71 MAPT (0.45) KDM4EALDH1A1MAPTTDP1KMT2A
SCHEMBL6840370 0.71 ALDH1A1 (0.60) KDM4EALDH1A1MAPTTDP1CHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11679996-B2 Ferro-cavitation processes for target metal separation NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2023-06-20 US disclosed
US-20220169541-A1 FERRO-CAVITATION PROCESSES FOR TARGET METAL SEPARATION NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2022-06-02 US disclosed
US-20210087079-A1 FERRO-CAVITATION PROCESSES FOR TARGET METAL SEPARATION NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2021-03-25 US disclosed
EP-3515572-A1 FERRO-CAVITATION PROCESSES FOR TARGET METAL SEPARATION National Research Council of Canada (CA) 2019-07-31 EP disclosed
WO-2018053630-A1 FERRO-CAVITATION PROCESSES FOR TARGET METAL SEPARATION NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2018-03-29 WO disclosed
US-7714319-B2 Organic thin film transistor IDEMITSU KOSAN CO., LTD. (JP) 2010-05-11 US disclosed
US-7714319-B2 Organic thin film transistor IDEMITSU KOSAN CO., LTD. (JP) 2010-05-11 US disclosed
US-20070120111-A1 Organic thin film transistor IDEMITSU KOSAN CO., LTD. (JP) 2007-05-31 US disclosed
US-20070120111-A1 Organic thin film transistor IDEMITSU KOSAN CO., LTD. (JP) 2007-05-31 US disclosed