Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | CCR2 | P41597 | 5/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.50 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4177737 | 0.82 | TAS1R3 (0.74) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL14198236 | 0.82 | TAS1R3 (0.74) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL14460307 | 0.79 | RAB9A (0.97) | NPC1RAB9AUSP2HPGDCTDSP1 | |
| SCHEMBL5666371 | 0.77 | RAB9A (1.00) | NPC1RAB9AUSP2HPGDCTDSP1 | |
| SCHEMBL11806 | 0.75 | NPC1 (0.85) | NPC1RAB9AUSP2HDAC8HDAC6 | |
| SCHEMBL25863591 | 0.74 | NPC1 (0.53) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL12515199 | 0.73 | DDB1 (0.56) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6783466 | 0.72 | UNG (0.54) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10605827 | 0.72 | HDAC8 (0.65) | NPC1RAB9ATAS1R3TAS1R1LMNA | |
| SCHEMBL23573449 | 0.72 | NPC1 (0.78) | NPC1RAB9ALMNAUSP2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152438-A1 | AMPHIPHILIC MOLECULAR MODULES AND CONSTRUCTS BASED THEREON | COVALENT PARTNERS LLC | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152438-A1 | AMPHIPHILIC MOLECULAR MODULES AND CONSTRUCTS BASED THEREON | ANXA6, THEM6, ANXA5 | NPC1 1566/4885RAB9A 4409/4885CCR2 823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.