Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3992652 | 0.78 | TLR4 (0.47) | TLR4CYP19A1 | |
| SCHEMBL3992657 | 0.78 | TLR4 (0.47) | TLR4CYP19A1 | |
| SCHEMBL3986049 | 0.78 | TLR4 (0.36) | TLR4 | |
| SCHEMBL3986044 | 0.78 | TLR4 (0.36) | TLR4 | |
| SCHEMBL3986003 | 0.72 | TLR4 (0.40) | TLR4CYP19A1 | |
| SCHEMBL3983907 | 0.72 | TLR4 (0.40) | TLR4CYP19A1 | |
| SCHEMBL2016163 | 0.69 | ALDH1A1 (0.37) | — | |
| SCHEMBL13531606 | 0.67 | TLR4 (0.31) | TLR4 | |
| SCHEMBL13531605 | 0.67 | TLR4 (0.31) | TLR4 | |
| SCHEMBL2693006 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7713989-B2 | Glucocorticoid receptor modulators | DOW ROBERT L | 2010-05-11 | — | — | US | disclosed |
| US-20070117805-A1 | Glucocorticoid receptor modulators | PFIZER INC. | 2007-05-24 | — | — | US | disclosed |
| US-7166593-B2 | Glucocorticoid receptor modulators | PFIZER, INC. (US) | 2007-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117805-A1 | Glucocorticoid receptor modulators | NR3C1, NR3C2, MC2R | TLR4 148/4885CYP19A1 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.