SCHEMBL1332730

SCHEMBL1332730

CCC(C(=O)O)C(O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
TDP1 Q9NUW8 2/20 0.42
CHRM1 P11229 1/20 0.42
AKR1A1 P14550 1/20 0.42
CHRM3 P20309 1/20 0.42
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
ADRA1A P35348 1/20 0.42
HRH1 P35367 1/20 0.42
DRD3 P35462 1/20 0.42
SLC6A3 Q01959 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC2 Q92769 1/20 0.42
TP53 P04637 1/20 0.38
CYP2C9 P11712 1/20 0.37
PDE4A P27815 1/20 0.37
CA2 P00918 1/20 0.36
MAPK1 P28482 1/20 0.36
GPR84 Q9NQS5 3/20 0.34
SLC1A3 P43003 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19584915 1.00 TSHR (0.47) TSHRTDP1CHRM1AKR1A1CHRM3
SCHEMBL15256667 1.00 TSHR (0.47) TSHRTDP1CHRM1AKR1A1CHRM3
Cadaverine Tartrate SCHEMBL29124598 0.82 TSHR (0.48) TSHRTDP1CHRM1AKR1A1CHRM3
SCHEMBL13249669 0.82 TSHR (0.41) TSHRTDP1CHRM1AKR1A1CHRM3
SCHEMBL13761133 0.82 TDP1 (0.50) TDP1CHRM1AKR1A1CHRM3HTR2A
SCHEMBL4756190 0.82 TDP1 (0.50) TDP1CHRM1AKR1A1CHRM3HTR2A
SCHEMBL1604267 0.82 TDP1 (0.50) TDP1CHRM1AKR1A1CHRM3HTR2A
SCHEMBL353854 0.80
SCHEMBL11440142 0.79 TDP1 (0.48) TDP1CHRM1AKR1A1CHRM3HTR2A
SCHEMBL11439361 0.79 TDP1 (0.48) TDP1CHRM1AKR1A1CHRM3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170152529-A1 Biological Production of Multi-Carbon Compounds from Methane INTREXON CORPORATION (US) 2017-06-01 US claimed
US-20140273128-A1 Biological Conversion of Multi-Carbon Compounds from Methane INTREXON CORPORATION (US) 2014-09-18 US claimed
US-20130225663-A1 LIPID DELIVERY FORMULATIONS DICERNA PHARMACEUTICALS, INC. (US) 2013-08-29 US claimed
WO-2011109294-A1 LIPID DELIVERY FORMULATIONS DICERNA PHARMACEUTICALS, INC. (US) 2011-09-09 WO claimed
US-12595494-B2 Biological production of multi-carbon compounds from methane BIOVERDE TECH LLC (US) 2026-04-07 US disclosed
US-20250027093-A1 MOLECULAR SWITCHES PRECIGEN, INC. (US) 2025-01-23 US disclosed
US-20240368638-A1 Biological Production of Multi-Carbon Compounds from Methane INTREXON CORPORATION 2024-11-07 US disclosed
US-12091667-B2 Molecular switches PRECIGEN, INC. (US) 2024-09-17 US disclosed
US-11821019-B2 Biological production of multi-carbon compounds from methane PRECIGEN, INC. (US) 2023-11-21 US disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
EP-3080285-B1 PROCESSES TO PREPARE ELONGATED 2-KETOACIDS AND C6-C10 COMPOUNDS THEREFROM VIA GENETIC MODIFICATIONS TO MICROBIAL METABOLIC PATHWAYS DOW GLOBAL TECHNOLOGIES LLC (US) 2022-07-27 EP disclosed
US-20220112506-A1 MOLECULAR SWITCHES PRECIGEN, INC. (US) 2022-04-14 US disclosed
US-5070151-A THERMOPLASTIC RESIN BLENDS OF POLYPHENYLENE ETHERS AND POLYLAC TAMS SUMITOMO CHEMICAL CO., LTD. (JP) 1991-12-03 US disclosed
EP-0456259-A1 Thermoplastic resin composition and article comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-11-13 EP disclosed
US-5019615-A Polyphenylene ether/polyester blend with nitrodiamine compound SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1991-05-28 US disclosed
US-5017663-A Polyphenylene ether, polyamide blend SUMITOMO CHEMICAL CO., LTD. (JP) 1991-05-21 US disclosed
EP-0394016-A2 Resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-10-24 EP disclosed
EP-0391733-A2 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-10-10 EP disclosed
EP-0382548-A2 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-08-16 EP disclosed
EP-0368283-A2 Resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-05-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595494-B2 Biological production of multi-carbon compounds from methane MLYCD, ADH1C, DERA TSHR 3786/4885TDP1 283/4885CHRM1 3123/4885
US-20130225663-A1 LIPID DELIVERY FORMULATIONS LIPA, LIPC, CETP TSHR 4015/4885TDP1 4612/4885CHRM1 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.