Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1334979 | 0.82 | HCRTR1 (0.58) | MEN1KMT2AALDH1A1HSD17B10HCRTR1 | |
| SCHEMBL1334981 | 0.82 | HCRTR1 (0.58) | MEN1KMT2AALDH1A1HSD17B10HCRTR1 | |
| SCHEMBL697414 | 0.79 | MEN1 (0.50) | MEN1KMT2AALDH1A1HSD17B10SIGMAR1 | |
| SCHEMBL16796874 | 0.78 | HCRTR2 (0.64) | MEN1KMT2AHCRTR1HCRTR2SIGMAR1 | |
| SCHEMBL3593539 | 0.76 | SIGMAR1 (0.40) | MEN1KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL3583885 | 0.76 | SIGMAR1 (0.40) | MEN1KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL1274526 | 0.75 | SIGMAR1 (0.39) | MEN1KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL1274649 | 0.75 | SIGMAR1 (0.39) | MEN1KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL16400695 | 0.74 | EHMT2 (0.47) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9771337 | 0.74 | CMA1 (0.50) | MEN1KMT2AALDH1A1SIGMAR1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110281854-A1 | MORPHOLINE COMPOUNDS | PFIZER INC | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110281854-A1 | MORPHOLINE COMPOUNDS | REN, MC2R, NR3C2 | MEN1 62/4885KMT2A 3182/4885ALDH1A1 3237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.