Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28349338 | 0.82 | ABCC4 (0.35) | ALDH1A1LMNA | |
| SCHEMBL1568673 | 0.80 | ALDH1A1 (0.32) | ALDH1A1LMNA | |
| SCHEMBL2028241 | 0.80 | ALDH1A1 (0.32) | ALDH1A1LMNA | |
| SCHEMBL5831688 | 0.80 | ALDH1A1 (0.58) | ALDH1A1LMNA | |
| SCHEMBL2027868 | 0.80 | ALDH1A1 (0.32) | ALDH1A1LMNA | |
| SCHEMBL9732270 | 0.78 | LMNA (0.35) | ALDH1A1LMNA | |
| SCHEMBL11093027 | 0.78 | LMNA (0.61) | ALDH1A1LMNA | |
| SCHEMBL9284591 | 0.78 | — | — | |
| SCHEMBL2541103 | 0.78 | — | — | |
| SCHEMBL45005 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160424-A1 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160424-A1 | RENIN INHIBITORS | ACE, REN, DNPEP | ALDH1A1 2175/4885LMNA 1952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.