Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.62 |
| ▸ | EIF4A1 | P60842 | 17/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | ABHD10 | Q9NUJ1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2629286 | 0.92 | PAX8 (0.74) | PAX8EIF4A1CYP3A4HIF1ANFKB1 | |
| SCHEMBL2629306 | 0.92 | EIF4A1 (0.51) | PAX8EIF4A1CYP3A4HIF1ANFKB1 | |
| SCHEMBL13329091 | 0.91 | EIF4A1 (0.73) | PAX8EIF4A1CYP3A4HIF1ANFKB1 | |
| SCHEMBL31123677 | 0.90 | EIF4A1 (0.75) | PAX8EIF4A1CYP3A4HIF1ANFKB1 | |
| SCHEMBL2629307 | 0.85 | PAX8 (0.84) | PAX8EIF4A1CYP3A4HIF1ANFKB1 | |
| Didesmethylrocaglamide SCHEMBL29520556 | 0.85 | EIF4A1 (0.83) | PAX8EIF4A1CYP3A4HIF1ANFKB1 | |
| Didesmethylrocaglamide SCHEMBL31489959 | 0.85 | EIF4A1 (0.83) | PAX8EIF4A1CYP3A4HIF1ANFKB1 | |
| SCHEMBL22773436 | 0.84 | EIF4A1 (0.74) | PAX8EIF4A1CYP3A4HIF1ANFKB1 | |
| SCHEMBL21275500 | 0.84 | EIF4A1 (0.74) | PAX8EIF4A1CYP3A4HIF1ANFKB1 | |
| SCHEMBL22773451 | 0.84 | EIF4A1 (0.74) | PAX8EIF4A1CYP3A4HIF1ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010060891-A1 | ROCAGLAOL DERIVATIVES AS CARDIOPROTECTANT AGENTS AND AS ANTINEOPLASTIC AGENTS | UNIVERSITE DE STRASBOURG (FR) | 2010-06-03 | — | — | WO | disclosed |