Didesmethylrocaglamide

Didesmethylrocaglamide

SCHEMBL29520556

COc1ccc([C@@]23Oc4cc(OC)cc(OC)c4[C@]2(O)[C@H](O)[C@H](C(N)=O)[C@H]3c2ccccc2)cc1

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EIF4A1 P60842 17/20 0.83
CYP3A4 P08684 1/20 0.83
HIF1A Q16665 1/20 0.83
NFKB1 P19838 1/20 0.80
RELA Q04206 1/20 0.80
PAX8 Q06710 1/20 0.69
ABHD10 Q9NUJ1 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Didesmethylrocaglamide SCHEMBL31489959 1.00 EIF4A1 (0.83) EIF4A1CYP3A4HIF1ANFKB1RELA
SCHEMBL22773451 0.94 EIF4A1 (0.74) EIF4A1CYP3A4HIF1ANFKB1RELA
SCHEMBL21275500 0.94 EIF4A1 (0.74) EIF4A1CYP3A4HIF1ANFKB1RELA
SCHEMBL22773436 0.94 EIF4A1 (0.74) EIF4A1CYP3A4HIF1ANFKB1RELA
SCHEMBL13329091 0.94 EIF4A1 (0.73) EIF4A1CYP3A4HIF1ANFKB1RELA
Rocagloic Acid SCHEMBL752143 0.92 EIF4A1 (0.86) EIF4A1CYP3A4HIF1ANFKB1RELA
Rocagloic Acid SCHEMBL29531721 0.92 EIF4A1 (0.86) EIF4A1CYP3A4HIF1ANFKB1RELA
SCHEMBL15079078 0.92 EIF4A1 (0.86) EIF4A1CYP3A4HIF1ANFKB1RELA
Rocagloic Acid SCHEMBL750035 0.92 EIF4A1 (0.86) EIF4A1CYP3A4HIF1ANFKB1RELA
Rocagloic Acid SCHEMBL31581598 0.92 EIF4A1 (0.86) EIF4A1CYP3A4HIF1ANFKB1RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023189909-A1 ROTOR AND ROTATING ELECTRIC MACHINE ニデック株式会社 2023-10-05 WO claimed
US-12565666-B2 Methods and compositions for modulating a genome FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2026-03-03 US disclosed
US-20250388609-A1 BIS(ORTHO-CARBORANYL)BORYL ANIONS AND METHODS FOR SYNTHESIS THEREOF BAYLOR UNIVERSITY (US) 2025-12-25 US disclosed
US-20250295625-A1 AGENT FOR PROMOTING ODONTOBLAST PROPAGATION AND DIFFERENTIATION SUN MEDICAL CO LTD (JP) 2025-09-25 US disclosed
CN-114919557-B Reducing brake vibrations due to rotor thickness variations 通用汽车环球科技运作有限责任公司 2024-04-12 CN disclosed
JP-2023144485-A ROTOR AND ROTARY ELECTRIC MACHINE ニデック株式会社 2023-10-11 JP disclosed
WO-2023189909-A1 ROTOR AND ROTATING ELECTRIC MACHINE ニデック株式会社 2023-10-05 WO disclosed
WO-2023189909-A1 ROTOR AND ROTATING ELECTRIC MACHINE ニデック株式会社 2023-10-05 WO disclosed
US-11711625-B2 Pixel array and image sensor including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-25 US disclosed
US-11579729-B2 Display device and method for operating the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-14 US disclosed
CN-115225833-A Pixel array and image sensor including the same 三星电子株式会社 2022-10-21 CN disclosed
US-20220337766-A1 PIXEL ARRAY AND IMAGE SENSOR INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-10-20 US disclosed
US-20220298501-A1 CRISPR-ASSOCIATED MU TRANSPOSASE SYSTEMS THE BROAD INSTITUTE, INC. (US) 2022-09-22 US disclosed
US-20220283690-A1 DISPLAY DEVICE AND METHOD FOR OPERATING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-09-08 US disclosed
EP-4049678-A1 AGENT FOR PROMOTING ODONTOBLAST PROPAGATION AND DIFFERENTIATION Sun Medical Co., Ltd. (JP) 2022-08-31 EP disclosed
CN-114919557-A Mitigating braking vibrations due to rotor thickness variations 通用汽车环球科技运作有限责任公司 2022-08-19 CN disclosed
US-20220258705-A1 MITIGATING BRAKING VIBRATION DUE TO ROTOR THICKNESS VARIATIONS GM Global Technology Operations LLC (US) 2022-08-18 US disclosed
CN-114746550-A Compositions and methods for modulating splicing and protein expression 斯托克制药公司 2022-07-12 CN disclosed
CN-114514010-A Odontoblast proliferation/differentiation promoter 尚美德齿科材料有限公司 2022-05-17 CN disclosed
CN-114253428-A Display device 三星显示有限公司 2022-03-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250295625-A1 AGENT FOR PROMOTING ODONTOBLAST PROPAGATION AND DIFFERENTIATION MKI67, MYADM, HGF EIF4A1 1719/4885CYP3A4 4876/4885HIF1A 680/4885
US-12565666-B2 Methods and compositions for modulating a genome RPRD2, ERN2, TPR EIF4A1 2225/4885CYP3A4 4505/4885HIF1A 3718/4885
US-20250388609-A1 BIS(ORTHO-CARBORANYL)BORYL ANIONS AND METHODS FOR SYNTHESIS THEREOF CHRND, CHRNE, BCOR EIF4A1 3742/4885CYP3A4 461/4885HIF1A 4298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.