Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11943181 | 0.84 | NR2F2 (0.47) | ALDH1A1MAPTDCTPP1NR2F2PDK2 | |
| SCHEMBL11943174 | 0.83 | MAPT (0.49) | ALDH1A1MAPTDCTPP1BCHEACHE | |
| SCHEMBL11943310 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTPKMDCTPP1 | |
| SCHEMBL11943238 | 0.77 | TP53 (0.42) | ALDH1A1MAPTDCTPP1CHRM4TSHR | |
| SCHEMBL11943270 | 0.76 | MAPT (0.48) | MAPTDCTPP1TSHRSMN1; SMN2LMNA | |
| SCHEMBL13329125 | 0.75 | FAAH (0.48) | MAPTPKMDCTPP1CHRM4TSHR | |
| SCHEMBL13304402 | 0.74 | SMN1; SMN2 (0.52) | ALDH1A1MAPTPKMTSHRSMN1; SMN2 | |
| SCHEMBL11943242 | 0.73 | DCTPP1 (0.53) | ALDH1A1MAPTDCTPP1TSHRSMN1; SMN2 | |
| SCHEMBL11943295 | 0.73 | MAPT (0.53) | ALDH1A1MAPTDCTPP1TSHRSMN1; SMN2 | |
| SCHEMBL11943261 | 0.73 | DCTPP1 (0.47) | ALDH1A1DCTPP1TSHRSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100158992-A1 | PIPERAZINE-SUBSTITUTED PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | SCHERING CORPORATION (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158992-A1 | PIPERAZINE-SUBSTITUTED PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | DPM1, GMPS, MAN2A1 | ALDH1A1 2003/4885MAPT 3651/4885PKM 190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.