Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 11/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 10/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 10/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 10/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 10/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13329484 | 1.00 | CHRM3 (0.39) | CHRM3SLC18A3CHRM2CHRM4CHRM5 | |
| SCHEMBL1109796 | 1.00 | CHRM3 (0.39) | CHRM3SLC18A3CHRM2CHRM4CHRM5 | |
| SCHEMBL3226320 | 0.89 | CHRM3 (0.39) | CHRM3SLC18A3CHRM2CHRM4CHRM5 | |
| SCHEMBL3226330 | 0.89 | CHRM3 (0.39) | CHRM3SLC18A3CHRM2CHRM4CHRM5 | |
| SCHEMBL13329443 | 0.89 | ALDH1A1 (0.40) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL1109822 | 0.89 | ALDH1A1 (0.40) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3218882 | 0.89 | ALDH1A1 (0.40) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL1109782 | 0.87 | CHRM3 (0.41) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL1109790 | 0.87 | CHRM3 (0.41) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL1109780 | 0.87 | CHRM3 (0.41) | CHRM3CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120277275-A1 | AZOLE AND THIAZOLE DERIVATIVES AND THEIR USE | PULMAGEN THERAPEUTICS (SYNERGY) LIMITED (GB) | 2012-11-01 | — | — | US | disclosed |
| US-20120277275-A1 | AZOLE AND THIAZOLE DERIVATIVES AND THEIR USE | PULMAGEN THERAPEUTICS (SYNERGY) LIMITED (GB) | 2012-11-01 | — | — | US | disclosed |
| US-20100113540-A1 | Azole and Thiazole Derivatives and Their Use | ARGENTA DISCOVERY LIMITED (GB) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113540-A1 | Azole and Thiazole Derivatives and Their Use | CHRM3, CHRM2, CHRM1 | CHRM3 1/4885SLC18A3 1960/4885CHRM2 2/4885 |
| US-20120277275-A1 | AZOLE AND THIAZOLE DERIVATIVES AND THEIR USE | CHRM3, GPR65, GPR34 | CHRM3 1/4885SLC18A3 1467/4885CHRM2 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.