Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL163753 | 0.86 | AKR1C3 (0.52) | PRKDCAKR1C3KMT2AMAPTL3MBTL1 | |
| SCHEMBL27165409 | 0.86 | AKR1C3 (0.52) | PRKDCAKR1C3KMT2AMAPTL3MBTL1 | |
| SCHEMBL16011397 | 0.81 | LMNA (0.41) | PRKDCKCNH2AKR1C3KMT2AMEN1 | |
| SCHEMBL30859286 | 0.79 | MEN1 (0.43) | PRKDCKCNH2KMT2AMEN1MAPT | |
| SCHEMBL27165401 | 0.79 | MEN1 (0.43) | PRKDCKCNH2KMT2AMEN1MAPT | |
| SCHEMBL30859290 | 0.79 | MEN1 (0.43) | PRKDCKCNH2KMT2AMEN1MAPT | |
| SCHEMBL28939782 | 0.79 | MEN1 (0.45) | AKR1C3KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL26629621 | 0.77 | AKR1C3 (0.52) | PRKDCAKR1C3KMT2AMEN1MAPT | |
| SCHEMBL7134286 | 0.76 | MAPT (0.51) | AKR1C3KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL25954140 | 0.76 | KMT2A (0.41) | AKR1C3KMT2AMEN1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718755-B1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL INC (US) | 2024-05-29 | — | — | EP | disclosed |
| US-8582192-B2 | Polarizing photochromic articles | TRANSITIONS OPTICAL, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-20110279883-A1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 2011-11-17 | — | — | US | disclosed |