Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13329801 | 0.92 | PIN1 (0.40) | PIN1 | |
| SCHEMBL13329796 | 0.88 | ALDH1A1 (0.42) | — | |
| SCHEMBL13330061 | 0.80 | PIN1 (0.36) | PIN1 | |
| SCHEMBL13070796 | 0.79 | ALDH1A1 (0.40) | — | |
| SCHEMBL510399 | 0.78 | ABCC2 (0.58) | ABCC2 | |
| SCHEMBL13329905 | 0.77 | ALDH1A1 (0.41) | PIN1 | |
| SCHEMBL3402954 | 0.76 | ABCC2 (0.69) | ABCC2 | |
| SCHEMBL3404865 | 0.76 | — | — | |
| SCHEMBL509316 | 0.75 | ABCC2 (0.49) | ABCC2 | |
| SCHEMBL403071 | 0.75 | ABCC2 (0.62) | ABCC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010067123-A1 | 2- (PIPERIDIN-1-YL) -4-HETEROCYCLYL-THIAZOLE-5-CARBOXYLIC ACID DERIVATIVES AGAINST BACTERIAL INFECTIONS | ASTRAZENECA AB (SE) | 2010-06-17 | — | — | WO | disclosed |