Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355372 | 0.92 | ALDH1A1 (0.35) | L3MBTL1AIMP2MC4RMTNR1B | |
| SCHEMBL13330866 | 0.89 | CYP3A4 (0.32) | L3MBTL1AIMP2CYP3A4 | |
| SCHEMBL13330843 | 0.88 | RAB9A (0.33) | AIMP2CYP3A4 | |
| SCHEMBL3354707 | 0.81 | ALDH1A1 (0.34) | AIMP2 | |
| SCHEMBL3359075 | 0.81 | ALDH1A1 (0.33) | CYP3A4 | |
| SCHEMBL3355341 | 0.80 | ALDH1A1 (0.34) | MC4RMTNR1B | |
| SCHEMBL3359004 | 0.80 | POLB (0.38) | L3MBTL1CYP3A4 | |
| SCHEMBL3353011 | 0.80 | LMNA (0.34) | L3MBTL1AIMP2MC4RMTNR1B | |
| SCHEMBL3358333 | 0.80 | ALDH1A1 (0.33) | MC4RMTNR1B | |
| SCHEMBL3352265 | 0.80 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068881-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-06-17 | — | — | WO | disclosed |