Dimethylamine

Dimethylamine

SCHEMBL1333133

CCC(CC)(CCCC(=O)O)C(=O)O.CNC

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CYP1A2 P05177 1/20 0.42
THRB P10828 1/20 0.42
AKR1B1 P15121 1/20 0.41
GPR84 Q9NQS5 7/20 0.40
PPARG P37231 7/20 0.40
PPARD Q03181 7/20 0.40
PPARA Q07869 7/20 0.40
HDAC11 Q96DB2 5/20 0.40
TSHR P16473 5/20 0.40
PTPN1 P18031 3/20 0.40
TLR2 O60603 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
FABP4 P15090 2/20 0.40
SLC22A6 Q4U2R8 2/20 0.40
SLC22A8 Q8TCC7 1/20 0.40
ESR1 P03372 1/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL41106 0.94 ALDH1A1 (0.47) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL27476414 0.92 ALDH1A1 (0.45) ALDH1A1MEN1KMT2ACYP1A2THRB
Diethylamine SCHEMBL341955 0.89 ALDH1A1 (0.40) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL1483105 0.88 AKR1B1 (0.50) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL18343637 0.86 AKR1B1 (0.45) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL14809032 0.86 GPR84 (0.52) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL8056020 0.86 GPR84 (0.52) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL3910055 0.86 GPR84 (0.52) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL14809975 0.86 GPR84 (0.52) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL910472 0.86 GPR84 (0.52) ALDH1A1MEN1KMT2ACYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3994192-B1 RESISTANT 2K-PUR COATINGS COVESTRO DEUTSCHLAND AG (DE) 2025-04-30 EP disclosed
EP-4277941-B1 COMPOSITIONS CONTAINING URETDIONE GROUPS COVESTRO DEUTSCHLAND AG (DE) 2025-01-01 EP disclosed
WO-2024119532-A1 POLYURETHANE PREPOLYMER COMPOSITION AND PREPARATION METHOD THEREFOR AND USE THEREOF 摩珈(上海)生物科技有限公司 2024-06-13 WO disclosed
EP-4157912-B1 COMPOSITIONS CONTAINING URETDIONE GROUPS CROSSLINKING AT LOW TEMPERATURES COVESTRO DEUTSCHLAND AG (DE) 2024-05-22 EP disclosed
EP-4277941-A1 COMPOSITIONS COMPRISING URETDIONES Covestro Deutschland AG (DE) 2023-11-22 EP disclosed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP disclosed
EP-3997183-B1 METHOD FOR THE PRODUCTION OF ISOCYANURATES FROM URETDIONES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-10-04 EP disclosed
WO-2022152536-A1 COMPOSITIONS COMPRISING URETDIONES COVESTRO DEUTSCHLAND AG (DE) 2022-07-21 WO disclosed
US-20210369911-A1 HYDROGEL COMPOSITIONS UNIVERSITÉ DE HAUTE-ALSACE (FR) 2021-12-02 US disclosed
US-20210332174-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2021-10-28 US disclosed
US-9458318-B2 Polyisocyanate mixtures COVESTRO DEUTSCHLAND AG (DE) 2016-10-04 US disclosed
EP-2841479-A1 LIGHTFAST POLYURETHANE COMPOSITIONS Bayer Materialscience AG (DE) 2015-03-04 EP disclosed
WO-2013160227-A1 LIGHTFAST POLYURETHANE COMPOSITIONS BAYER MATERIALSCIENCE AG (DE) 2013-10-31 WO disclosed
US-20130158145-A1 POLYURETHANE HAVING HIGH LIGHT REFRACTION BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-06-20 US disclosed
US-20130158146-A1 POLYISOCYANATE MIXTURES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-06-20 US disclosed
US-20130116357-A1 POLYURETHANE HAVING LOW VOLUME SHRINKAGE BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-05-09 US disclosed
US-20110281966-A1 POLYURETHANE SEALING COMPOUNDS COVESTRO DEUTSCHLAND AG (DE) 2011-11-17 US disclosed
US-20110281965-A1 POLYURETHANE CASTING COMPOUNDS Bayer MateialScience AG (DE) 2011-11-17 US disclosed
US-5196287-A PROCESS FOR PRODUCING ENCAPSULATED PHOTOSENSITIVE COMPOSITION BY ALTERING THE CONCENTRATION OF THE INTERNAL PHASE DURING ENCAPSULATION THE MEAD CORPORATION (US) 1993-03-23 US disclosed
US-4668734-A Stable dispersions of polyureas and/or polyhydrazo-dicarbonamides in relatively high molecular weight hydroxyl-group containing materials, a process for the production thereof and the use thereof for the production of polyurethane plastics BAYER AKTIENGESELLSCHAFT (DE) 1987-05-26 US disclosed