Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | SLC5A2 | P31639 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13332623 | 0.90 | LMNA (0.61) | LMNASMN1; SMN2TSHRSLC5A2ALDH1A1 | |
| SCHEMBL1170484 | 0.87 | LMNA (1.00) | LMNASMN1; SMN2TSHRSLC5A2ALDH1A1 | |
| SCHEMBL1521083 | 0.82 | ALDH1A1 (0.59) | TSHRALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL23241181 | 0.81 | LMNA (0.67) | LMNASMN1; SMN2TSHRSLC5A2ALDH1A1 | |
| SCHEMBL3205551 | 0.78 | LMNA (0.67) | LMNASMN1; SMN2TSHRSLC5A2ALDH1A1 | |
| SCHEMBL11712251 | 0.77 | LMNA (0.67) | LMNASMN1; SMN2TSHRSLC5A2ALDH1A1 | |
| SCHEMBL2497655 | 0.77 | LMNA (0.79) | LMNASMN1; SMN2TSHRSLC5A2ALDH1A1 | |
| SCHEMBL2475227 | 0.77 | LMNA (0.79) | LMNASMN1; SMN2TSHRSLC5A2ALDH1A1 | |
| SCHEMBL23241152 | 0.77 | LMNA (0.61) | LMNASMN1; SMN2TSHRSLC5A2ALDH1A1 | |
| Bromide SCHEMBL11709807 | 0.76 | LMNA (0.69) | LMNASMN1; SMN2TSHRSLC5A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010067067-A1 | COMPOUNDS FOR TREATING CANCER | EVOTEC AG (DE) | 2010-06-17 | — | — | WO | disclosed |