Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25472935 | 0.79 | ADORA1 (0.44) | ADORA1ADORA2AYTHDC1CDK1CYP1A2 | |
| SCHEMBL12923695 | 0.76 | ADORA2A (0.50) | ADORA1ADORA2ACCR1CCR5CCR8 | |
| SCHEMBL800728 | 0.72 | ADORA1 (0.46) | ADORA1ADORA2AYTHDC1CCR1CCR5 | |
| SCHEMBL3933146 | 0.72 | PI4KA (0.51) | — | |
| SCHEMBL441875 | 0.70 | ADORA1 (0.62) | ADORA1ADORA2AYTHDC1CDK1CYP1A2 | |
| SCHEMBL27404283 | 0.68 | CCR1 (0.34) | ADORA1ADORA2ACCR1CCR5CCR8 | |
| SCHEMBL25667797 | 0.68 | ALDH1A1 (0.42) | ADORA1ADORA2AGRM5 | |
| SCHEMBL14196788 | 0.67 | CDK1 (0.44) | ADORA1ADORA2AYTHDC1CDK1CCNB1 | |
| SCHEMBL13011009 | 0.67 | CCR1 (0.47) | CCR1CCR5CCR8HSP90AA1 | |
| SCHEMBL12332534 | 0.67 | ADORA1 (0.48) | ADORA1ADORA2AYTHDC1CDK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120706-A1 | Macrolides Useful Against Inflammatory and Allergic Diseases | BASILEA PHARMACEUTICA AG (CH) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120706-A1 | Macrolides Useful Against Inflammatory and Allergic Diseases | HRH4, HRH2, IL4 | ADORA1 789/4885ADORA2A 1843/4885YTHDC1 2105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.