Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 3/20 | 0.51 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.51 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.40 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.40 |
| ▸ | GAK | O14976 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12628673 | 0.76 | PI4KA (0.58) | PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL17691571 | 0.70 | HTT (0.56) | FGFR1SRCHTT | |
| SCHEMBL13731216 | 0.70 | XDH (0.52) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL5146335 | 0.68 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL9150129 | 0.68 | PI4KA (0.66) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL25878225 | 0.68 | PI4KA (0.49) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL25878226 | 0.68 | PI4KA (0.60) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL22431902 | 0.68 | CYP2D6 (0.55) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL28298222 | 0.68 | ADORA2A (0.58) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL3236039 | 0.67 | EGFR (0.51) | PI4KAPI4K2BPI4K2API4KBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044033-A1 | A REGIOSELECTIVE PALLADIUM CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | Sanofi-Aventis (FR) | 2009-04-08 | — | — | EP | claimed |
| WO-2008009348-A1 | A REGIOSELECTIVE PALLADIUM CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI-AVENTIS (FR) | 2008-01-24 | — | — | WO | claimed |