Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13336481 | 0.97 | GPR119 (0.48) | GPR119USP30MAPTLMNAGAA | |
| SCHEMBL13336503 | 0.88 | USP30 (0.40) | GPR119USP30 | |
| SCHEMBL13336491 | 0.87 | SMN1; SMN2 (0.41) | GPR119USP30MAPTLMNATHRB | |
| SCHEMBL2936390 | 0.83 | GPR119 (0.62) | GPR119 | |
| SCHEMBL2936389 | 0.83 | GPR119 (0.62) | GPR119 | |
| SCHEMBL19400799 | 0.81 | USP30 (0.57) | GPR119USP30MAPTGAATHRB | |
| SCHEMBL2937900 | 0.80 | GPR119 (0.62) | GPR119 | |
| SCHEMBL12506046 | 0.77 | MAPT (0.46) | GPR119USP30MAPTGAATHRB | |
| SCHEMBL13336504 | 0.77 | USP30 (0.42) | GPR119USP30 | |
| SCHEMBL13336497 | 0.77 | GPR119 (0.38) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120807-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120807-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GPR65, GPR39 | GPR119 1/4885USP30 3054/4885MAPT 3590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.