SCHEMBL1333875

SCHEMBL1333875

c1ccc(C2NCCOC2c2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.65
SLC6A3 Q01959 2/20 0.65
ADRA1A P35348 1/20 0.65
HTR2B P41595 1/20 0.65
TACR1 P25103 7/20 0.48
CHRNA7 P36544 1/20 0.46
CYP2D6 P10635 1/20 0.43
SLC6A4 P31645 1/20 0.43
KCNH2 Q12809 1/20 0.43
SLC18A3 Q16572 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
HTR1A P08908 1/20 0.41
CYP2C19 P33261 1/20 0.41
NLRP3 Q96P20 1/20 0.41
GBA1 P04062 1/20 0.40
TSHR P16473 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11141618 0.81 SLC6A2 (0.61) SLC6A2SLC6A3ADRA1AHTR2BTACR1
SCHEMBL20105596 0.81 SLC6A2 (0.61) SLC6A2SLC6A3ADRA1AHTR2BTACR1
Hydrochloric Acid SCHEMBL15922321 0.79 SLC6A2 (0.59) SLC6A2SLC6A3ADRA1AHTR2BTACR1
Hydrochloric Acid SCHEMBL15921747 0.79 SLC6A2 (0.59) SLC6A2SLC6A3ADRA1AHTR2BTACR1
Hydrochloric Acid SCHEMBL15921749 0.79 SLC6A2 (0.59) SLC6A2SLC6A3ADRA1AHTR2BTACR1
SCHEMBL28526425 0.79 SLC6A2 (0.44) SLC6A2SLC6A3ADRA1AHTR2BSLC18A3
SCHEMBL3458744 0.78 SLC6A2 (0.62) SLC6A2SLC6A3ADRA1AHTR2BTACR1
Phenmetrazine SCHEMBL15154744 0.78 SLC6A2 (1.00) SLC6A2SLC6A3ADRA1AHTR2BTACR1
Phenmetrazine SCHEMBL8094204 0.78 SLC6A2 (1.00) SLC6A2SLC6A3ADRA1AHTR2BTACR1
Phenmetrazine SCHEMBL15159760 0.78 SLC6A2 (1.00) SLC6A2SLC6A3ADRA1AHTR2BTACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115784474-A High-temperature-resistant high-pressure-resistant phosphorus-free sodium-free or low-sodium scale and corrosion inhibitor for boiler and preparation method and application thereof 上海聚焓能源科技有限公司 2023-03-14 CN claimed
US-4803200-A SHIPPING FEVER SYNDROME A. H. ROBINS COMPANY, INCORPORATED (US) 1989-02-07 US claimed
CN-115784474-A High-temperature-resistant high-pressure-resistant phosphorus-free sodium-free or low-sodium scale and corrosion inhibitor for boiler and preparation method and application thereof 上海聚焓能源科技有限公司 2023-03-14 CN disclosed
EP-2569310-A1 MORPHOLINE COMPOUNDS AS MINERALOCORTICOID RECEPTOR ANTAGONISTS Pfizer Inc (US) 2013-03-20 EP disclosed
US-20110281854-A1 MORPHOLINE COMPOUNDS PFIZER INC 2011-11-17 US disclosed
WO-2011141848-A1 MORPHOLINE COMPOUNDS AS MINERALOCORTICOID RECEPTOR ANTAGONISTS PFIZER INC. (US) 2011-11-17 WO disclosed
US-4803200-A SHIPPING FEVER SYNDROME A. H. ROBINS COMPANY, INCORPORATED (US) 1989-02-07 US disclosed
US-4384968-A TREATING GAS STREAM WITH MORPHOLINE OR SERIVATIVE BETZ LABORATORIES, INC. (US) 1983-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110281854-A1 MORPHOLINE COMPOUNDS REN, MC2R, NR3C2 SLC6A2 966/4885SLC6A3 1447/4885ADRA1A 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.