Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.75 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12302023 | 1.00 | LMNA (0.75) | LMNAADKTDP1THRBSMN1; SMN2 | |
| SCHEMBL285059 | 1.00 | LMNA (0.75) | LMNAADKTDP1THRBSMN1; SMN2 | |
| SCHEMBL12302015 | 1.00 | LMNA (0.75) | LMNAADKTDP1THRBSMN1; SMN2 | |
| SCHEMBL12945763 | 1.00 | LMNA (0.75) | LMNAADKTDP1THRBSMN1; SMN2 | |
| SCHEMBL12029798 | 1.00 | LMNA (0.75) | LMNAADKTDP1THRBSMN1; SMN2 | |
| SCHEMBL8196421 | 1.00 | LMNA (0.75) | LMNAADKTDP1THRBSMN1; SMN2 | |
| SCHEMBL285464 | 0.99 | LMNA (0.73) | LMNAADKTDP1THRBSMN1; SMN2 | |
| SCHEMBL8992747 | 0.99 | LMNA (0.73) | LMNAADKTDP1THRBSMN1; SMN2 | |
| SCHEMBL16508681 | 0.99 | LMNA (0.73) | LMNAADKTDP1THRBSMN1; SMN2 | |
| SCHEMBL16508671 | 0.99 | LMNA (0.73) | LMNAADKTDP1THRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065586-A2 | PREPARATION OF CAPECITABINE | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-06-10 | — | — | WO | disclosed |