Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | ADK | P55263 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16508681 | 1.00 | LMNA (0.73) | LMNAADKTDP1NAAATHRB | |
| SCHEMBL16508671 | 1.00 | LMNA (0.73) | LMNAADKTDP1NAAATHRB | |
| SCHEMBL8992747 | 1.00 | LMNA (0.73) | LMNAADKTDP1NAAATHRB | |
| SCHEMBL12302015 | 0.99 | LMNA (0.75) | LMNAADKTDP1NAAATHRB | |
| SCHEMBL12945763 | 0.99 | LMNA (0.75) | LMNAADKTDP1NAAATHRB | |
| SCHEMBL12302023 | 0.99 | LMNA (0.75) | LMNAADKTDP1NAAATHRB | |
| SCHEMBL8196421 | 0.99 | LMNA (0.75) | LMNAADKTDP1NAAATHRB | |
| SCHEMBL12029798 | 0.99 | LMNA (0.75) | LMNAADKTDP1NAAATHRB | |
| SCHEMBL13340646 | 0.99 | LMNA (0.75) | LMNAADKTDP1NAAATHRB | |
| SCHEMBL285059 | 0.99 | LMNA (0.75) | LMNAADKTDP1NAAATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428213-A1 | STABILIZED CHLORITE SOLUTIONS IN COMBINATION WITH FLUOROPYRIMIDINES FOR USE IN CANCER TREATMENT | Nuvo Research AG (CH) | 2012-03-14 | — | — | EP | claimed |
| EP-0602454-B1 | N-Oxycarbonyl substituted 5'-deoxy-5-fluorocytidines | HOFFMANN LA ROCHE (CH) | 1996-04-24 | — | — | EP | claimed |
| EP-0602454-A1 | N-Oxycarbonyl substituted 5'-deoxy-5-fluorocytidines | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-22 | — | — | EP | claimed |
| EP-2428213-A1 | STABILIZED CHLORITE SOLUTIONS IN COMBINATION WITH FLUOROPYRIMIDINES FOR USE IN CANCER TREATMENT | Nuvo Research AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| EP-0602454-B1 | N-Oxycarbonyl substituted 5'-deoxy-5-fluorocytidines | HOFFMANN LA ROCHE (CH) | 1996-04-24 | — | — | EP | disclosed |
| EP-0602454-A1 | N-Oxycarbonyl substituted 5'-deoxy-5-fluorocytidines | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-22 | — | — | EP | disclosed |