Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 13/20 | 0.33 |
| ▸ | CDK2 | P24941 | 13/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.32 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.32 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13432627 | 0.90 | THRB (0.38) | THRBCDK1CDK2CCNA2SUMO2 | |
| SCHEMBL13387173 | 0.90 | THRB (0.41) | THRBCDK1CDK2CCNA2SUMO2 | |
| SCHEMBL13340911 | 0.87 | ENPP2 (0.35) | SUMO2SUMO1SENP7SENP2GLO1 | |
| SCHEMBL12053267 | 0.87 | THRB (0.38) | THRBCDK1CDK2CCNA2SUMO2 | |
| SCHEMBL14075509 | 0.86 | THRB (0.34) | THRBCDK1CDK2CA2 | |
| SCHEMBL13340928 | 0.86 | TDP1 (0.37) | MEN1KMT2AMAPTPTGS1TDP1 | |
| SCHEMBL13340457 | 0.85 | THRB (0.33) | THRBCDK1CDK2CA2 | |
| SCHEMBL13340997 | 0.82 | CA12 (0.36) | THRBCDK1CDK2CCNA2SUMO2 | |
| SCHEMBL13340989 | 0.82 | CA12 (0.36) | THRBCDK1CDK2CCNA2SUMO2 | |
| SCHEMBL12053370 | 0.81 | SENP2 (0.48) | THRBCDK1CDK2SUMO2SUMO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7708786-B2 | Dye mixtures of fiber-reactive azo dyes, their preparation and use | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2010-05-04 | — | — | US | disclosed |
| US-20090025152-A1 | DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND USE | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2009-01-29 | — | — | US | disclosed |
| US-7455699-B2 | Dye mixtures of fiber-reactive azo dyes, their preparation and use | DYSTAR TEXILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2008-11-25 | — | — | US | disclosed |
| US-20070271711-A1 | Dye Mixtures of Fibre-Reactive Azo Dyes Production and Use Thereof | DYSTAR TEXTILFARBEN GMBH & CO., DEUTSCHLAND KG (DE) | 2007-11-29 | — | — | US | disclosed |