SCHEMBL133438

SCHEMBL133438

[CH2]CCCCCCCCCCCCCCCCC[CH]Nc1ccc(C)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.36
DHODH Q02127 1/20 0.35
ALDH1A1 P00352 4/20 0.34
NPC1 O15118 3/20 0.34
ALOX12 P18054 2/20 0.34
RAB9A P51151 2/20 0.34
TGM2 P21980 1/20 0.33
HDAC3 O15379 2/20 0.33
HDAC1 Q13547 2/20 0.33
HDAC2 Q92769 2/20 0.33
HDAC10 Q969S8 2/20 0.33
HDAC11 Q96DB2 2/20 0.33
HDAC8 Q9BY41 2/20 0.33
HDAC6 Q9UBN7 2/20 0.33
NCOR2 Q9Y618 1/20 0.33
POLB P06746 1/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5077120 0.84 HTT (0.40) MAPTDHODHALDH1A1NPC1ALOX12
SCHEMBL132640 0.81 ALDH1A1 (0.39) MAPTALDH1A1NPC1ALOX12RAB9A
SCHEMBL16972621 0.81 ALDH1A1 (0.39) MAPTALDH1A1NPC1ALOX12RAB9A
SCHEMBL5077122 0.72 MAPT (0.61) MAPTALDH1A1HDAC1POLBMEN1
SCHEMBL2093052 0.72 MAPT (0.61) MAPTALDH1A1HDAC1POLBMEN1
SCHEMBL2088459 0.69 MAPT (0.64) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL2092431 0.67 MAPT (0.67) MAPTALDH1A1NPC1RAB9APOLB
SCHEMBL5142158 0.67 SOAT2 (0.50) ALDH1A1GAAHTT
SCHEMBL2926348 0.65
SCHEMBL135471 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230366197-A1 Cementitious Panels with Swellable Materials and Methods of Providing a Moisture or Water Barrier in Cementitious Panels Using Swellable Materials BANK OF AMERICA, N.A., AS COLLATERAL AGENT 2023-11-16 US disclosed
US-11801662-B2 Cementitious panels with polymeric-film facing material GOLD BOND BUILDING PRODUCTS, LLC (US) 2023-10-31 US disclosed
US-11708692-B2 Cementitious panels with swellable materials and methods of providing a moisture or water barrier in cementitious panels using swellable materials GOLD BOND BUILDING PRODUCTS, LLC (US) 2023-07-25 US disclosed
EP-3105053-B1 THIN NANOCOMPOSITE FILM FOR USE IN AN ABSORBENT ARTICLE KIMBERLY CLARK CO (US) 2021-09-22 EP disclosed
US-11058791-B2 Thin nanocomposite film for use in an absorbent article KIMBERLY-CLARK WORLDWIDE, INC. (US) 2021-07-13 US disclosed
US-10869790-B2 Absorbent article package with reduced noise KIMBERLY-CLARK WORLDWIDE, INC. (US) 2020-12-22 US disclosed
US-10849800-B2 Film with reduced noise for use in an absorbent article KIMBERLY-CLARK WORLDWIDE, INC. (US) 2020-12-01 US disclosed
US-20200208398-A1 Cementitious Panels with Swellable Materials and Methods of Providing a Moisture or Water Barrier in Cementitious Panels Using Swellable Materials BANK OF AMERICA, N.A., AS COLLATERAL AGENT 2020-07-02 US disclosed
US-20200207060-A1 Cementitious Panels with Polymeric-Film Facing Material BANK OF AMERICA, N.A., AS COLLATERAL AGENT 2020-07-02 US disclosed
EP-3099733-B1 NANOCOMPOSITE PACKAGING FILM KIMBERLY CLARK CO (US) 2020-05-06 EP disclosed
US-6632868-B2 Nanocomposite concentrate of a intercalated layered silicate dispersed uniformly throughout a matrix polymer blend of a polyolefin and a maleic anhydride-modified polyolefin; heat resistance, tensile strength AMCOL INTERNATIONAL CORPORATION 2003-10-14 US disclosed
US-6462122-B1 NANOCOMPOSITE CONCENTRATE OF A LAYERED SILICATE DISPERSED UNIFORMLY IN MATRIX POLYMER; INCREASED TENSILE STRENGTH; REDUCED HEAT DEGRADATION OF POLYMER; MOLDING MATERIALS; EXTRUDED FILMS AND LAMINATES; FOOD PACKAGING AMCOL INTERNATIONAL CORPORATION 2002-10-08 US disclosed
US-6407155-B1 LAYERED SILICATE DISPERSED UNIFORMILY THROUGH MATRIX; DUCTILITY, TENSILE STRENGTH, FLEXIBILITY AMCOL INTERNATIONAL CORPORATION 2002-06-18 US disclosed
US-6399690-B2 MATRIX POLYMER; SWELLABLE LAYERS; OXIDATION RESISTANCE AMCOL INTERNATIONAL CORPORATION 2002-06-04 US disclosed
US-20010033924-A1 Intercalates formed with polypropylene/maleic anhydride-modified polypropylene intercalants JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2001-10-25 US disclosed
US-20010025076-A1 Layered compositions with multi-charged onium ions as exchange cations, and their application to prepare monomer, oligomer, and polymer intercalates and nanocomposites prepared with the layered compositions of the intercalates AMCOL INTERNATIONAL CORPORATION 2001-09-27 US disclosed
US-6232388-B1 CONTROLLING CONCENTRATION AMCOL INTERNATIONAL CORPORATION 2001-05-15 US disclosed
US-6225394-B1 USEFUL FOR BARRIER LAYERS IN MULTI-PACKAGING AND FOR COATINGS AMCOL INTERNATIONAL CORPORATION 2001-05-01 US disclosed
EP-1038834-A1 Surface modified layered silicate material and compositions containing the same AMCOL INTERNATIONAL CORPORATION (US) 2000-09-27 EP disclosed
WO-2000009605-A1 INTERCALATES FORMED WITH MXD6 NYLON INTERCALANTS AMCOL INTERNATIONAL CORPORATION (US) 2000-02-24 WO disclosed