Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12199721 | 0.82 | RAB9A (0.53) | ALDH1A1GAARAB9AKDM4EKMT2A | |
| SCHEMBL12680943 | 0.75 | RAB9A (0.60) | ALDH1A1GAARAB9AKDM4EKMT2A | |
| SCHEMBL5154581 | 0.75 | SIGMAR1 (0.50) | POLB | |
| SCHEMBL17934007 | 0.73 | RAD52 (0.61) | ALDH1A1GAARAB9AKDM4EKMT2A | |
| SCHEMBL16129354 | 0.69 | ALDH1A1 (0.53) | ALDH1A1GAARAB9AKDM4EKMT2A | |
| SCHEMBL16129355 | 0.69 | ALDH1A1 (0.61) | ALDH1A1GAARAB9AKDM4EKMT2A | |
| SCHEMBL16217190 | 0.67 | MEN1 (0.59) | GAARAB9AKMT2ANPC1MAPT | |
| SCHEMBL19087069 | 0.66 | SIGMAR1 (0.48) | ALDH1A1GAATP53POLB | |
| SCHEMBL3536301 | 0.66 | GAA (0.69) | ALDH1A1GAARAB9AKDM4EKMT2A | |
| SCHEMBL16603052 | 0.66 | NPC1 (0.67) | ALDH1A1GAARAB9AKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010071822-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2010-06-24 | — | — | WO | disclosed |