Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122573 | 0.85 | POLB (0.63) | NPC1RAB9AGAAKMT2APOLB | |
| SCHEMBL28872280 | 0.79 | HIF1A (0.54) | NPC1RAB9AHIF1APTPN1GAA | |
| SCHEMBL5723907 | 0.77 | MTNR1A (0.56) | HIF1APTPN1ALDH1A1 | |
| SCHEMBL3275628 | 0.77 | NPC1 (0.72) | NPC1RAB9AGAATAAR1HPGD | |
| SCHEMBL5726195 | 0.77 | MTNR1A (0.67) | HSD17B10NPC1RAB9AGAATAAR1 | |
| SCHEMBL20766321 | 0.75 | ALDH1A1 (0.56) | NPC1RAB9AHPGDALDH1A1HTT | |
| SCHEMBL27102271 | 0.75 | HPGD (0.43) | NPC1RAB9AGAATAAR1KMT2A | |
| SCHEMBL5108159 | 0.75 | NPC1 (0.69) | HSD17B10NPC1RAB9AGAATAAR1 | |
| SCHEMBL717950 | 0.75 | HPGD (0.63) | HSD17B10NPC1RAB9APTPN1GAA | |
| SCHEMBL28872227 | 0.74 | HIF1A (0.49) | HSD17B10HIF1APTPN1TAAR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723266-B2 | Substituted aryl sulphony(thio)ureas used as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2010-05-25 | — | — | US | disclosed |