Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | KLK7 | P49862 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13729624 | 0.91 | LMNA (0.49) | LMNAMEN1MAPTKMT2AATM | |
| SCHEMBL9208258 | 0.83 | LMNA (0.85) | LMNAMEN1MAPTKMT2AATM | |
| SCHEMBL12131984 | 0.81 | LMNA (0.65) | LMNAMEN1MAPTKMT2AATM | |
| SCHEMBL27471005 | 0.81 | LMNA (0.81) | LMNAMEN1MAPTKMT2AATM | |
| SCHEMBL1058293 | 0.80 | LMNA (0.68) | LMNAMEN1MAPTKMT2AATM | |
| SCHEMBL1759107 | 0.80 | LMNA (0.68) | LMNAMEN1MAPTKMT2AATM | |
| SCHEMBL9362750 | 0.80 | LMNA (0.58) | LMNAMEN1MAPTKMT2AATM | |
| SCHEMBL4570313 | 0.80 | LMNA (0.72) | LMNAMEN1MAPTKMT2AATM | |
| SCHEMBL12532828 | 0.80 | LMNA (0.72) | LMNAMEN1MAPTKMT2AATM | |
| SCHEMBL12133169 | 0.79 | LMNA (0.71) | LMNAMEN1MAPTKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723327-B2 | Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease | CARDAX PHARMACEUTICALS, INC. (US) | 2010-05-25 | — | — | US | disclosed |
| US-7592449-B2 | Structural carotenoid analogs for the inhibition and amelioration of disease | CARDAX PHARMACEUTICALS, INC. (US) | 2009-09-22 | — | — | US | disclosed |
| US-7320997-B2 | Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease | CARDAX PHARMACEUTICALS, INC. (US) | 2008-01-22 | — | — | US | disclosed |
| US-7320997-B2 | Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease | CARDAX PHARMACEUTICALS, INC. (US) | 2008-01-22 | — | — | US | disclosed |
| US-7317008-B2 | Carotenoid ester analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury | CARDAX PHARMACEUTICALS, INC. (US) | 2008-01-08 | — | — | US | disclosed |