Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.30 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13345753 | 0.91 | LMNA (0.62) | LMNAPOLBMEN1MAPTKMT2A | |
| SCHEMBL27469061 | 0.81 | LMNA (0.67) | LMNAPOLBMAPTALDH1A1LPAR1 | |
| SCHEMBL19942153 | 0.80 | LMNA (0.41) | LMNAPOLBMEN1MAPTKMT2A | |
| SCHEMBL10074419 | 0.80 | DNM1 (0.36) | LMNA | |
| SCHEMBL19941929 | 0.80 | LMNA (0.34) | LMNA | |
| SCHEMBL19335250 | 0.79 | LMNA (0.41) | LMNA | |
| SCHEMBL28397505 | 0.78 | ALDH1A1 (0.47) | LMNAPOLBALDH1A1 | |
| SCHEMBL9362289 | 0.78 | LMNA (0.46) | LMNAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL420322 | 0.78 | LMNA (0.53) | LMNAPOLBALDH1A1LPAR1LPAR3 | |
| SCHEMBL8335902 | 0.78 | LMNA (0.53) | LMNAPOLBALDH1A1LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401918-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING BIODEGRADABLE POLY(BETA-AMINO ESTERS) | MASSACHUSETTS INST TECHNOLOGY (US) | 2018-03-07 | — | — | EP | disclosed |
| WO-2009097349-A1 | THERAPEUTIC COMPOSITIONS | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2009-08-06 | — | — | WO | disclosed |
| WO-2008011561-A2 | END-MODIFIED POLY(BETA-AMINO ESTERS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-01-24 | — | — | WO | disclosed |
| WO-2007143659-A2 | CROSSLINKED, DEGRADABLE POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-12-13 | — | — | WO | disclosed |