SCHEMBL13345970

SCHEMBL13345970

CCOC(=O)[C@H](Cc1ccc(O)cc1)N(Cl)C(C)C[C@@H]1OC[C@@H](O)C(O)[C@H]1O

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.32
C5AR1 P21730 2/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
TYR P14679 2/20 0.31
BACE1 P56817 1/20 0.31
CHRM2 P08172 4/20 0.31
CHRM3 P20309 4/20 0.31
CHRM1 P11229 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13346949 0.91 MMP8 (0.37) C5AR1
SCHEMBL13346952 0.82
SCHEMBL16476074 0.80
SCHEMBL13345968 0.77
SCHEMBL24894079 0.68 ALDH1A1 (0.30)
SCHEMBL11783130 0.67 PTGS2 (0.46) PTGS2ESR1ESR2BACE1
SCHEMBL11783121 0.67 PTGS2 (0.46) PTGS2ESR1ESR2BACE1
SCHEMBL6718148 0.67 ESR1 (0.45) PTGS2ESR1ESR2BACE1
SCHEMBL13295462 0.64 PRKD3 (0.33)
SCHEMBL2434150 0.64 ESR1 (0.50) PTGS2ESR1ESR2BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2373670-B1 NOVEL AMINO SUBSTITUTED C-GLYCOSIDE DERIVATIVES AND USE THEREOF AS COSMETIC OREAL (FR) 2014-04-16 EP disclosed
WO-2010063953-A2 NOVEL AMINO C-XYLOSIDE COMPOUNDS, AND COSMETIC USE L'OREAL (FR) 2010-06-10 WO disclosed