SCHEMBL13346362

SCHEMBL13346362

CC(=O)CC1C2C=CC(C2)C1CC(C)=O

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 3/20 0.36
▸ TDP1 Q9NUW8 2/20 0.36
▸ APEX1 P27695 1/20 0.36
▸ SMN1; SMN2 Q16637 3/20 0.33
▸ ALDH1A1 P00352 3/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ RAB9A P51151 1/20 0.32
▸ PKM P14618 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ MEN1 O00255 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13370702 0.92 POLB (0.31) POLBTDP1APEX1SMN1; SMN2ALDH1A1
SCHEMBL13346355 0.88 ALDH1A1 (0.32) ALDH1A1MAPK1
SCHEMBL13346342 0.88 — —
SCHEMBL3294508 0.87 POLB (0.31) POLBTDP1APEX1SMN1; SMN2ALDH1A1
SCHEMBL13370694 0.86 ALDH1A1 (0.36) POLBTDP1APEX1SMN1; SMN2ALDH1A1
SCHEMBL3295539 0.86 ALDH1A1 (0.33) POLBTDP1APEX1ALDH1A1MEN1
SCHEMBL13346356 0.85 ACHE (0.31) ALDH1A1
SCHEMBL3293814 0.82 — —
SCHEMBL13346372 0.81 SMN1; SMN2 (0.33) POLBTDP1APEX1SMN1; SMN2L3MBTL1
SCHEMBL5848235 0.78 HSD11B1 (0.48) POLBTDP1APEX1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7714087-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2010-05-11 — — US disclosed
US-7714087-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2010-05-11 — — US disclosed
EP-1734061-B1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer and uses thereof MITSUI CHEMICALS INC (JP) 2010-04-07 — — EP disclosed
US-20090137757-A1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof IMUTA JUNICHI 2009-05-28 — — US disclosed
US-20090137757-A1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof IMUTA JUNICHI 2009-05-28 — — US disclosed
US-7393907-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2008-07-01 — — US disclosed
US-7393907-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2008-07-01 — — US disclosed
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