Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 4/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | PDE8B | O95263 | 3/20 | 0.31 |
| ▸ | PTPRF | P10586 | 1/20 | 0.31 |
| ▸ | PTPRA | P18433 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14102236 | 0.75 | CDK1 (0.49) | CDK1CCNB1CCNE1CDK2PDE8B | |
| SCHEMBL22704876 | 0.75 | CDK1 (0.38) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL13788521 | 0.72 | TP53 (0.30) | — | |
| SCHEMBL763189 | 0.69 | ADORA2A (0.53) | ADORA2AADORA3 | |
| SCHEMBL4841951 | 0.67 | DHFR (0.36) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL4046792 | 0.66 | PNP (0.51) | — | |
| SCHEMBL7940046 | 0.62 | ADORA2A (0.48) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL25423776 | 0.62 | CDK1 (0.37) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL16259901 | 0.61 | ALDH1A1 (0.41) | — | |
| SCHEMBL14471200 | 0.60 | LRRK2 (0.33) | CDK1CCNB1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718374-B2 | Single nucleotide polymorphism analysis of highly polymorphic target sequences | ELITECH HOLDING B.V. (NL) | 2010-05-18 | — | — | US | disclosed |
| US-20090087922-A1 | SINGLE NUCLEOTIDE POLYMORPHISM ANALYSIS OF HIGHLY POLYMORPHIC TARGET SEQUENCES | EPOCH BIOSCIENCES, INC. (US) | 2009-04-02 | — | — | US | disclosed |
| US-7348146-B2 | Single nucleotide polymorphism analysis of highly polymorphic target sequences | EPOCH BIOSCIENCES, INC. (US) | 2008-03-25 | — | — | US | disclosed |