Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 5/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938906 | 0.79 | ADORA2A (0.45) | ADORA2ADHFRPIK3CGMAPTCDK1 | |
| SCHEMBL16093989 | 0.79 | LMNA (0.46) | ADORA2ADHFRMAPTBLMKMT2A | |
| SCHEMBL9237679 | 0.76 | ADORA2A (0.54) | ADORA2ADHFRPIK3CGMEN1MAPT | |
| SCHEMBL3291956 | 0.74 | ADORA2A (0.52) | ADORA2ADHFRPIK3CGMEN1MAPT | |
| SCHEMBL21983360 | 0.74 | KDM4E (0.43) | ADORA2AMEN1MAPTKMT2ACDK2 | |
| SCHEMBL33841 | 0.72 | DCPS (0.38) | ADORA2ACDK2CASP1DCPSPDPK1 | |
| SCHEMBL21138122 | 0.69 | ADORA2A (0.33) | ADORA2ADHFRCDK1CCNB1CCNE1 | |
| Hydrochloric Acid SCHEMBL19858969 | 0.69 | DCPS (0.36) | ADORA2ACDK2CASP1DCPSPDPK1 | |
| SCHEMBL12158710 | 0.69 | LMNA (0.41) | ADORA2AMEN1MAPTKMT2AKDM4E | |
| Bromide SCHEMBL62599 | 0.69 | DCPS (0.36) | ADORA2ACDK2CASP1DCPSPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232312-B1 | ADMINISTERING A COMBINATION OF INDENE AND PYRIMIDO(5,4-D)PYRIMIDINE DERIVATIVES TO TREAT PREPANCREATIC CANCER | CELL PATHWAYS, INC. | 2001-05-15 | — | — | US | disclosed |