Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | SNCA | P37840 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 9/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.57 |
| ▸ | NPC1 | O15118 | 8/20 | 0.53 |
| ▸ | RAB9A | P51151 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14431305 | 0.89 | NPC1 (0.62) | MAPTSNCAESR1ESR2NPC1 | |
| SCHEMBL13496378 | 0.89 | MAPT (0.55) | MAPTSNCAESR1ESR2NPC1 | |
| SCHEMBL4307744 | 0.86 | MAPT (0.51) | MAPTSNCAESR1ESR2NPC1 | |
| Ammonia Solution, Strong SCHEMBL17024437 | 0.84 | MAPT (0.50) | MAPTSNCAESR1ESR2NPC1 | |
| SCHEMBL15723573 | 0.82 | MAPT (0.55) | MAPTSNCAESR1ESR2NPC1 | |
| SCHEMBL10424044 | 0.82 | NPC1 (0.60) | MAPTSNCAESR1ESR2NPC1 | |
| SCHEMBL17024443 | 0.81 | MAPT (0.70) | MAPTSNCAESR1ESR2NPC1 | |
| SCHEMBL12209688 | 0.81 | RAB9A (0.77) | MAPTSNCAESR1ESR2NPC1 | |
| SCHEMBL13254489 | 0.81 | ESR2 (0.77) | MAPTSNCAESR1ESR2NPC1 | |
| SCHEMBL14030787 | 0.80 | MAPT (0.51) | MAPTSNCAESR1ESR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100119822-A1 | CARBON NANOTUBE COPOLYMERS AND COMPOSITIONS AND METHODS OF USING THE SAME | SPIRIT AEROSYSTEMS, INC. (US) | 2010-05-13 | — | — | US | disclosed |