Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17024443 | 0.89 | MAPT (0.70) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL4307744 | 0.86 | MAPT (0.51) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| Ammonia Solution, Strong SCHEMBL17024437 | 0.85 | MAPT (0.50) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL13347357 | 0.82 | MAPT (0.59) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL14030787 | 0.81 | MAPT (0.51) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL14030790 | 0.79 | MAPT (0.50) | MAPTRAB9ASMN1; SMN2TP53SNCA | |
| SCHEMBL14431305 | 0.79 | NPC1 (0.62) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL13496378 | 0.79 | MAPT (0.55) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL14030845 | 0.77 | MAPT (0.50) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL14030833 | 0.75 | HDAC6 (0.48) | MAPTRAB9ASMN1; SMN2TP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9725424-B2 | 4-(5-amino-6-hydroxybenzoxazol-2-yl) ammonium benzoate and preparation method and use thereof | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2017-08-08 | — | — | US | disclosed |
| WO-2014075403-A1 | 4-(5-AMINO-6-HYDROXYBENZOXAZOL-2-YL)AMMONIUM BENZOATE AND PREPARATION METHOD AND USE THEREOF | 浙江工业大学 (CN) | 2014-05-22 | — | — | WO | disclosed |