Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.50 |
| ▸ | ESR1 | P03372 | 4/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL17024437 | 0.99 | MAPT (0.50) | MAPTSNCAESR2ESR1TTR | |
| SCHEMBL14030787 | 0.95 | MAPT (0.51) | MAPTSNCAESR2ESR1TTR | |
| SCHEMBL14030790 | 0.90 | MAPT (0.50) | MAPTSNCAESR2ESR1TTR | |
| SCHEMBL14030833 | 0.86 | HDAC6 (0.48) | MAPTSNCATTRALBMAOA | |
| SCHEMBL15723573 | 0.86 | MAPT (0.55) | MAPTSNCAESR2ESR1RAB9A | |
| SCHEMBL14030812 | 0.86 | GPR119 (0.55) | MAPTSNCAESR2ESR1TTR | |
| SCHEMBL14030788 | 0.86 | MAPT (0.52) | MAPTSNCAESR2ESR1RAB9A | |
| SCHEMBL13347357 | 0.86 | MAPT (0.59) | MAPTSNCAESR2ESR1RAB9A | |
| SCHEMBL9797251 | 0.85 | TTR (0.60) | MAPTSNCAESR2ESR1TTR | |
| SCHEMBL14030845 | 0.85 | MAPT (0.50) | MAPTSNCAESR2ESR1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9725424-B2 | 4-(5-amino-6-hydroxybenzoxazol-2-yl) ammonium benzoate and preparation method and use thereof | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2017-08-08 | — | — | US | claimed |
| US-20150239856-A1 | 4-(5-Amino-6-Hydroxybenzoxazol-2-YL) Ammonium Benzoate and Preparation Method and Use Thereof | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2015-08-27 | — | — | US | claimed |
| US-9725424-B2 | 4-(5-amino-6-hydroxybenzoxazol-2-yl) ammonium benzoate and preparation method and use thereof | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2017-08-08 | — | — | US | disclosed |
| US-9725424-B2 | 4-(5-amino-6-hydroxybenzoxazol-2-yl) ammonium benzoate and preparation method and use thereof | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2017-08-08 | — | — | US | disclosed |
| US-9725424-B2 | 4-(5-amino-6-hydroxybenzoxazol-2-yl) ammonium benzoate and preparation method and use thereof | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2017-08-08 | — | — | US | disclosed |
| US-9725424-B2 | 4-(5-amino-6-hydroxybenzoxazol-2-yl) ammonium benzoate and preparation method and use thereof | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2017-08-08 | — | — | US | disclosed |
| US-20150239856-A1 | 4-(5-Amino-6-Hydroxybenzoxazol-2-YL) Ammonium Benzoate and Preparation Method and Use Thereof | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2015-08-27 | — | — | US | disclosed |
| US-20150239856-A1 | 4-(5-Amino-6-Hydroxybenzoxazol-2-YL) Ammonium Benzoate and Preparation Method and Use Thereof | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2015-08-27 | — | — | US | disclosed |
| US-20150239856-A1 | 4-(5-Amino-6-Hydroxybenzoxazol-2-YL) Ammonium Benzoate and Preparation Method and Use Thereof | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2015-08-27 | — | — | US | disclosed |
| US-20150239856-A1 | 4-(5-Amino-6-Hydroxybenzoxazol-2-YL) Ammonium Benzoate and Preparation Method and Use Thereof | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2015-08-27 | — | — | US | disclosed |
| CN-102942533-B | Preparation method of 4-(5-amino-6-hydroxy-2-benzoxazolyl) benzoic acid (ABA) | YANCHENG DRAGON CHEMICAL CO LTD | 2015-01-28 | — | — | CN | disclosed |
| CN-101372532-A | Use of 5-amino-6-hydroxy-2-(p-carboxyphenyl)benzoxazole salt | UNIV ZHEJIANG TECHNOLOGY (CN) | 2009-02-25 | — | — | CN | disclosed |
| US-7495106-B1 | O-aminophenol-containing AB-monomer for heterocyclic rigid-rod polymers | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2009-02-24 | — | — | US | disclosed |
| US-20080269455-A1 | Process for Production of Polybenzazole Polymer and the Polymer | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2008-10-30 | — | — | US | disclosed |
| US-20080269455-A1 | Process for Production of Polybenzazole Polymer and the Polymer | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2008-10-30 | — | — | US | disclosed |
| US-20080269455-A1 | Process for Production of Polybenzazole Polymer and the Polymer | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2008-10-30 | — | — | US | disclosed |
| CN-101016275-A | 5-amino-6-hydroxy-2- (p-carboxyphenyl) benzoxazole salt, synthesis and application | UNIV ZHEJIANG TECHNOLOGY (CN) | 2007-08-15 | — | — | CN | disclosed |
| US-5610261-A | COMPRESSIVE STRENGTH, PARA-ORIENTED BENZOXAZOLE CONDENSATION POLYMERS WITH TETRACARBOXY-SUBSTITUTED ADAMANTANE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1997-03-11 | — | — | US | disclosed |
| US-5426173-A | Polybenzoxazoles having improved compressive strength | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1995-06-20 | — | — | US | disclosed |
| US-5426173-A | Polybenzoxazoles having improved compressive strength | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1995-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239856-A1 | 4-(5-Amino-6-Hydroxybenzoxazol-2-YL) Ammonium Benzoate and Preparation Method and Use Thereof | HAAO, ABAT, HAO2 | MAPT 868/4885SNCA 2157/4885ESR2 4189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.