Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3856726 | 0.84 | AKR1B1 (0.52) | AKR1B1GAAKDM4EMAPTHPGD | |
| SCHEMBL8984192 | 0.83 | CA2 (0.56) | AKR1B1GAAKDM4EMAPTHPGD | |
| SCHEMBL25741028 | 0.82 | AKR1B1 (0.46) | AKR1B1GAAKDM4EMAPTHPGD | |
| SCHEMBL583915 | 0.81 | AKR1B1 (0.60) | AKR1B1GAAKDM4EMAPTHPGD | |
| SCHEMBL13347362 | 0.80 | PTGDR (0.42) | AKR1B1GAAKDM4EMAPTHPGD | |
| SCHEMBL11278615 | 0.80 | PTGDR (0.42) | AKR1B1GAAKDM4EMAPTHPGD | |
| Phenylacetic Acid SCHEMBL27901933 | 0.79 | AKR1B1 (0.68) | AKR1B1GAALMNATSHRHSD17B10 | |
| SCHEMBL19062614 | 0.79 | PTGS1 (0.56) | AKR1B1GAAKDM4EMAPTHPGD | |
| SCHEMBL11786434 | 0.78 | XDH (0.41) | AKR1B1GAAKDM4EMAPTHPGD | |
| SCHEMBL215399 | 0.78 | XDH (0.50) | AKR1B1GAAKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140155640-A1 | Surface Functionalised Nanoparticles | NANOCO TECHNOLOGIES LTD. (GB) | 2014-06-05 | — | — | US | disclosed |
| US-8394976-B2 | Surface functionalised nanoparticles | Nanoco Technologies, Ltd. (GB) | 2013-03-12 | — | — | US | disclosed |
| US-20100113813-A1 | SURFACE FUNCTIONALISED NANOPARTICLES | NANOCO TECHNOLOGIES LIMITED (GB) | 2010-05-06 | — | — | US | disclosed |
| US-20100068522-A1 | Surface Functionalised Nanoparticles | NANOCO TECHNOLOGIES LIMITED (GB) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155640-A1 | Surface Functionalised Nanoparticles | EPCAM, L1CAM, CD4 | AKR1B1 3491/4885GAA 283/4885KDM4E 3228/4885 |
| US-20100113813-A1 | SURFACE FUNCTIONALISED NANOPARTICLES | CD47, CD63, EPCAM | AKR1B1 4466/4885GAA 2306/4885KDM4E 1608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.