Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389545 | 0.89 | PTGDR (0.38) | PTGDRPTGDR2POLBKDM4EMAPT | |
| SCHEMBL13347362 | 0.85 | PTGDR (0.42) | PTGDRPTGDR2POLBKDM4EMAPT | |
| SCHEMBL7937253 | 0.82 | KEAP1 (0.41) | PTGDRPTGDR2KDM4EGABRA1GABRB2 | |
| SCHEMBL8422007 | 0.81 | GAA (0.58) | POLBKDM4EMAPTTDP1RGS12 | |
| SCHEMBL13347366 | 0.80 | AKR1B1 (0.43) | PTGDRPTGDR2POLBKDM4EMAPT | |
| SCHEMBL2461750 | 0.80 | XDH (0.48) | POLBKDM4EMAPTGAAHPGD | |
| SCHEMBL7042257 | 0.80 | HSP90AB1 (0.54) | POLBKDM4EMAPTGAAHPGD | |
| SCHEMBL11660801 | 0.78 | GABRA1 (0.45) | POLBKDM4EMAPTGAAHPGD | |
| SCHEMBL9489328 | 0.78 | DHFR (0.48) | POLBKDM4EMAPTGAAHPGD | |
| SCHEMBL4373039 | 0.77 | ALDH1A1 (0.52) | POLBKDM4EMAPTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009866-B1 | PHENOLIC ESTERAMIDE ANTIOXIDANTS AND THEIR USE | UNIROYAL, INC. (US) | 1982-08-04 | — | — | EP | disclosed |
| US-4305868-A | Phenolic esteramide antioxidants | UNIROYAL, INC. (US) | 1981-12-15 | — | — | US | disclosed |
| US-4304714-A | Polyfunctional phenolic oxamide antioxidants | UNIROYAL, INC. (US) | 1981-12-08 | — | — | US | disclosed |
| EP-0009866-A1 | Phenolic esteramide antioxidants and their use | UNIROYAL, INC. (US) | 1980-04-16 | — | — | EP | disclosed |